▪ Abstract Parkinson's disease (PD) is an age-related neurodegenerative disorder that
affects approximately 1 million persons in the United States. It is characterized by resting …

The basal ganglia circuitry processes the signals that flow from the cortex, allowing the
correct execution of voluntary movements. In Parkinson's disease, the degeneration of …

DNA damage is the prime activator of the enzyme poly (ADP-ribose) polymerase1 (PARP-1)
whose overactivation has been proven to be associated with the pathogenesis of numerous …

Parkinson's disease (PD) is increasingly recognized as a neurodegenerative disorder
strongly associated with environmental chemical exposures. Recent epidemiological data …

ETHNOPHARMACOLOGICAL RELEVANCE: Ginsenosides, the major active ingredients of
Panax ginseng, produce a variety of pharmacological or physiological responses with …

Treatment of glaucoma continues to be directed at lowering intraocular pressure to decrease
the likelihood of disease progression. In the future intraocular pressure reduction might be …

Abstract The neurotoxin 6‐hydroxydopamine (6‐OHDA) has been used extensively in
animal models of Parkinson's disease. Typically, rodents develop severe unilateral …

We examined effects of two insulin‐like growth factors, insulin and insulin‐like growth factor‐
I (IGF‐I), against apoptosis, excitotoxicity, and free radical neurotoxicity in cortical cell …

This book explores the many prospects, challenges and ethical questions that surround the
engineering of our reproductive cells. It is an accessible, three-part examination, moving …

Dieses Buch vermittelt einen kompetenten und fächerübergreifenden Überblick über das
aktuelle Wissen auf dem Gebiet der Parkinson-Krankheit. Es ist im deutschsprachigen …