[HTML][HTML] Regulatory T cell and macrophage crosstalk in acute lung injury: future perspectives

T Guan, X Zhou, W Zhou, H Lin - Cell death discovery, 2023 - nature.com
Acute lung injury (ALI) describes the injury to endothelial cells in the lungs and associated
vessels due to various factors. Furthermore, ALI accompanied by inflammation and …

[HTML][HTML] Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms

R Zhu, T Yan, Y Feng, Y Liu, H Cao, G Peng, Y Yang… - Cell research, 2021 - nature.com
The infusion of coronavirus disease 2019 (COVID-19) patients with mesenchymal stem cells
(MSCs) potentially improves clinical symptoms, but the underlying mechanism remains …

[HTML][HTML] Animal models of acute exacerbation of pulmonary fibrosis

X Ye, M Zhang, H Gu, M Liu, Y Zhao, Y Shi, S Wu… - Respiratory …, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive scarring interstitial lung disease
with an unknown cause. Some patients may experience acute exacerbations (AE), which …

Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway

Y Wang, X Wang, Y Li, Z Xue, R Shao, L Li, Y Zhu… - Pharmacological …, 2022 - Elsevier
The pathogenic hyper-inflammatory response has been revealed as the major cause of the
severity and death of the Corona Virus Disease 2019 (COVID-19). Xuanfei Baidu Decoction …

[HTML][HTML] Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury

R Zhao, L Wang, T Wang, P Xian, H Wang… - Journal of Controlled …, 2022 - Elsevier
Mesenchymal stem cell-derived small extracellular vesicles (MSC-EVs) are promising
nanotherapeutic agent for pneumonia (bacterial origin, COVID-19), but the optimal …

Lung targeted liposomes for treating ARDS

SA Raviv, M Alyan, E Egorov, A Zano… - Journal of controlled …, 2022 - Elsevier
Abstract Acute Respiratory Distress Syndrome (ARDS), associated with Covid-19 infections,
is characterized by diffuse lung damage, inflammation and alveolar collapse that impairs …

[HTML][HTML] Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling

JS Bednash, VE Kagan, JA Englert, D Farkas… - Translational …, 2022 - Elsevier
The acute respiratory distress syndrome (ARDS) is a common complication of severe COVID-
19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory syndrome …

[HTML][HTML] Salidroside attenuates acute lung injury via inhibition of inflammatory cytokine production

D Song, M Zhao, L Feng, P Wang, Y Li, W Li - Biomedicine & …, 2021 - Elsevier
Acute lung injury is a fatal condition characterized by excessive inflammation responses.
Salidroside, the active constituent of Rhodiola rosea, possesses properties including anti …

[HTML][HTML] Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway

Y Zhu, Q Han, L Wang, B Wang, J Chen, B Cai… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Acute lung injury (ALI) is one of the fatal complications of
respiratory virus infections such as influenza virus and coronavirus, which has high clinical …

Beneficial effects of aloperine on inflammation and oxidative stress by suppressing necroptosis in lipopolysaccharide-induced acute lung injury mouse model

YR Cui, F Qu, WJ Zhong, HH Yang, J Zeng, JH Huang… - Phytomedicine, 2022 - Elsevier
Rationale Alveolar epithelial cell death, inflammation, and oxidative stress are typical
features of acute lung injury (ALI). Aloperine (Alo), an alkaloid isolated from Sophora …