Skeletal aging
Aging represents the single greatest risk factor for chronic diseases, including osteoporosis,
a skeletal fragility syndrome that increases fracture risk. Optimizing bone strength throughout …
a skeletal fragility syndrome that increases fracture risk. Optimizing bone strength throughout …
Insights and implications of sexual dimorphism in osteoporosis
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
DNAzyme nanoconstruct-integrated autonomously-adaptive coatings enhance titanium-implant osteointegration by cooperative angiogenesis and vessel remodeling
M Chen, M Li, X Ren, F Zhou, Y Li, L Tan, Z Luo… - ACS …, 2023 - ACS Publications
Orthopedic implants have a high failure rate due to insufficient interfacial osseointegration,
especially under osteoporotic conditions. Type H vessels are CD31+ EMCN+ capillaries …
especially under osteoporotic conditions. Type H vessels are CD31+ EMCN+ capillaries …
[HTML][HTML] S-sulfhydration of SIRT3 combats BMSC senescence and ameliorates osteoporosis via stabilizing heterochromatic and mitochondrial homeostasis
F Liu, L Yuan, L Li, J Yang, J Liu, Y Chen… - Pharmacological …, 2023 - Elsevier
Senescence of bone marrow mesenchymal stem cells (BMSCs) is one of the leading causes
of osteoporosis. SIRT3, an essential NAD-dependent histone deacetylase, is highly …
of osteoporosis. SIRT3, an essential NAD-dependent histone deacetylase, is highly …
The role of trace elements and minerals in osteoporosis: a review of epidemiological and laboratory findings
The objective of the present study was to review recent epidemiological and clinical data on
the association between selected minerals and trace elements and osteoporosis, as well as …
the association between selected minerals and trace elements and osteoporosis, as well as …
A narrative review of diabetic bone disease: Characteristics, pathogenesis, and treatment
B Wu, Z Fu, X Wang, P Zhou, Q Yang… - Frontiers in …, 2022 - frontiersin.org
Recently, the increasing prevalence of diabetes mellitus has made it a major chronic illness
which poses a substantial threat to human health. The prevalence of osteoporosis among …
which poses a substantial threat to human health. The prevalence of osteoporosis among …
Purine metabolism-related genes and immunization in thyroid eye disease were validated using bioinformatics and machine learning
Z Wu, Y Gao, L Cao, Q Peng, X Yao - Scientific Reports, 2023 - nature.com
Thyroid eye disease (TED), an autoimmune inflammatory disorder affecting the orbit,
exhibits a range of clinical manifestations. While the disease presentation can vary, cases …
exhibits a range of clinical manifestations. While the disease presentation can vary, cases …
Classical and nonclassical manifestations of primary hyperparathyroidism
G El‐Hajj Fuleihan, M Chakhtoura… - Journal of Bone and …, 2020 - academic.oup.com
This narrative review summarizes data on classical and nonclassical manifestations of
primary hyperparathyroidism (PHPT). It is based on a rigorous literature search, inclusive of …
primary hyperparathyroidism (PHPT). It is based on a rigorous literature search, inclusive of …
Synergistic Osteogenic and Antiapoptotic Framework Nucleic Acid Complexes Prevent Diabetic Osteoporosis
L Bai, M Feng, Q Zhang, Z Cai, Q Li, Y Li… - Advanced Functional …, 2024 - Wiley Online Library
Diabetes mellitus (DM) is characterized by elevated blood glucose and advanced glycation
end product (AGEs) levels. Increased AGEs in bone tissue inhibit osteogenic differentiation …
end product (AGEs) levels. Increased AGEs in bone tissue inhibit osteogenic differentiation …
Computational Study of the Interaction of C12P12 and C12N12 Nanocages with Alendronate Drug Molecule
The utilization of nanomaterials as efficient delivery systems to specific metabolic sites is
essential for harnessing the utmost therapeutic potency of drugs leading to a tremendous …
essential for harnessing the utmost therapeutic potency of drugs leading to a tremendous …