Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation.
The presence of autoantibodies in the sera of RA patients has provided many clues to the …

A key unanswered question in the pathophysiology of rheumatoid arthritis (RA) is how
systemic autoimmunity progresses to joint-specific inflammation. In patients with seropositive …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …

Patients with rheumatoid arthritis (RA) have historically developed progressive damage of
articular bone and cartilage, which correlates with disability over time. In addition, these …

Objective Anti-carbamylated protein (anti-CarP) antibodies are reported to associate with
more radiographic progression within the total rheumatoid arthritis (RA) population and anti …

In the pathogenesis of several rheumatic diseases, such as rheumatoid arthritis,
spondyloarthritis, osteoarthritis, osteoporosis, alterations in osteoblast growth, differentiation …

Background Identification of risk factors for rapid joint destruction in early rheumatoid arthritis
(RA) can be helpful for optimizing treatment, and improving our understanding of destructive …

Rheumatoid arthritis (RA) is a disease of the joints that causes decreased quality of life.
Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with possible use …

Background Anti-citrullinated protein antibodies (ACPAs) are the hallmark of rheumatoid
arthritis (RA). Protein citrullination is believed to drive autoantigen selection in RA …

The last two decades have marked a growing understanding of the interaction occurring
between bone and immune cells. The chronic inflammation and immune system dysfunction …