Circular RNAs and cervical cancer: friends or foes? A landscape on circRNA-mediated regulation of key signaling pathways involved in the onset and progression of …

E Heydarnia, Z Dorostgou, N Hedayati… - Cell Communication and …, 2024 - Springer
Cervical cancer (CC) is a common gynecologic malignancy, accounting for a significant
proportion of women death worldwide. Human papillomavirus (HPV) infection is one of the …

[HTML][HTML] Flavonoids as modulators of miRNA expression in pancreatic cancer: Pathways, Mechanisms, And Therapeutic Potential

H Helen, MC Gunawan, P Halim, MR Dinata… - Biomedicine & …, 2024 - Elsevier
Pancreatic cancer (PC) is a complex malignancy, distinguished by its aggressive
characteristics and unfavorable prognosis. Recent developments in understanding the …

[HTML][HTML] The landscape of circRNAs in gliomas temozolomide resistance: Insights into molecular pathways

A Mafi, N Hedayati, S Kahkesh, S Khoshayand… - Non-coding RNA …, 2024 - Elsevier
As the deadliest type of primary brain tumor, gliomas represent a significant worldwide
health concern. Circular RNA (circRNA), a unique non-coding RNA molecule, seems to be …

[HTML][HTML] Ferroptosis contributes to the progression of female-specific neoplasms, from breast cancer to gynecological malignancies in a manner regulated by non …

K Hushmandi, DJ Klionsky, AR Aref, M Bonyadi… - Non-coding RNA …, 2024 - Elsevier
Ferroptosis, a recently identified type of non-apoptotic cell death, triggers the elimination of
cells in the presence of lipid peroxidation and in an iron-dependent manner. Indeed …

The potential role of circular RNAs-regulated PI3K signaling in non-small cell lung cancer: Molecular insights and clinical perspective

S Kahkesh, SM Khoshnazar, Y Gholinezhad… - … -Research and Practice, 2024 - Elsevier
Non-small cell lung cancer (NSCLC), accounting for more than 80% of all cases, is the
predominant form of lung cancer and the leading cause of cancer-related deaths worldwide …

The function and mechanism of circRNAs in 5-fluorouracil resistance in tumors: biological mechanisms and future potential

A Mafi, N Hedayati, YE Milasi, S Kahkesh… - … -Research and Practice, 2024 - Elsevier
Fluorouracil (5-FU) is a well-known chemotherapy drug extensively used in the treatment of
breast cancer. It works by inhibiting cancer cell proliferation and inducing cell death through …

A comprehensive review of the PTEN/PI3K/Akt axis in multiple myeloma: from molecular interactions to potential therapeutic targets

M Alimohammadi, P Rahimzadeh, R Khorrami… - … -Research and Practice, 2024 - Elsevier
Phosphatase and tensin homolog (PTEN), phosphatidylinositol 3-kinase (PI3K), and protein
kinase B (Akt) signaling pathways contribute to the development of several cancers …

The Dual Roles of circRNAs in Wnt/β-Catenin Signaling and Cancer Progression

WH Almalki, SS Almujri - Pathology-Research and Practice, 2024 - Elsevier
Cancer, a complex pathophysiological condition, arises from the abnormal proliferation and
survival of cells due to genetic mutations. Dysregulation of cell cycle control, apoptosis, and …

Regulating miRNAs Expression by Resveratrol: Novel Insights based on Molecular Mechanism and Strategies for Cancer Therapy.

A Keshavarzmotamed, V Mousavi… - Current Molecular …, 2023 - europepmc.org
Resveratrol, a polyphenolic phytoalexin found in a wide range of plants, including grapes,
berries, and peanuts, is an extensively researched phytochemical with unique …