In the human eye, a transparent cornea and lens combine to form the" refracton" to focus
images on the retina. This requires the refracton to have a high refractive index" n," mediated …

Aquaporins (AQPs) are a family of transmembrane water channels expressed in all living
organisms. AQPs facilitate osmotically driven water flux across biological membranes and …

High levels of reactive oxygen species such as hydrogen peroxide (H 2 O 2) cause oxidative
stress in the lens and lead to cataractogenesis. The present investigation was undertaken to …

Aging proteins in the lens become increasingly aggregated and insoluble, contributing to
presbyopia. In this study, we investigated the ability of aggrelyte‐2 (N, S‐diacetyl‐L‐cysteine …

Purpose: Presbyopia—the progressive loss of near focus with age—is primarily a result of
changes in lens biomechanics. In particular, the shape of the ocular lens in the absence of …

Cataract is a leading cause of blindness globally, and its surgical treatment poses a
significant burden on global healthcare. Pharmacologic therapies, including antioxidants …

Lens, an avascular tissue involved in light transmission, generates an internal
microcirculatory system to promote ion and fluid circulation, thus providing nutrients to …

Charged multivesicular-body protein 4b (CHMP4B) is a core sub-unit of the endosomal
sorting complex required for transport-III (ESCRT-III) machinery that serves myriad …

Cataract is the leading cause of blindness worldwide. Here, we reported a potential,
effective therapeutic mean for cataract prevention and treatment. Gap junction …

Connexins are the structural components of gap junctions and hemichannels that mediate
the communication and exchange of small molecules between cells, and between the …