[HTML][HTML] Chronic stress promotes cancer development

S Dai, Y Mo, Y Wang, B Xiang, Q Liao, M Zhou… - Frontiers in …, 2020 - frontiersin.org
Stress is an inevitable part of life. Chronic stress on account of reasons like adversity,
depression, anxiety, or loneliness/social isolation can endanger human health. Recent …

[HTML][HTML] Stress reduction strategies in breast cancer: Review of pharmacologic and non-pharmacologic based strategies

R Gosain, E Gage-Bouchard, C Ambrosone… - Seminars in …, 2020 - Springer
Breast cancer is the most common cancer diagnosed in women. It is associated with multiple
symptoms in both patients and caregivers, such as stress, anxiety, depression, sleep …

[HTML][HTML] Neurobiology of cancer: the role of β-adrenergic receptor signaling in various tumor environments

B Mravec, L Horvathova, L Hunakova - International journal of molecular …, 2020 - mdpi.com
The development and progression of cancer depends on both tumor micro-and
macroenvironments. In addition, psychosocial and spiritual “environments” might also affect …

[HTML][HTML] Chronic stress in solid tumor development: from mechanisms to interventions

J Yan, Y Chen, M Luo, X Hu, H Li, Q Liu… - Journal of Biomedical …, 2023 - Springer
Chronic stress results in disturbances of body hormones through the neuroendocrine
system. Cancer patients often experience recurrent anxiety and restlessness during disease …

[HTML][HTML] Adrenergic signaling: a targetable checkpoint limiting development of the antitumor immune response

G Qiao, M Chen, MJ Bucsek, EA Repasky… - Frontiers in …, 2018 - frontiersin.org
An immune response must be tightly controlled so that it will be commensurate with the level
of response needed to protect the organism without damaging normal tissue. The roles of …

A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic response

JWL Eng, KM Kokolus, CB Reed, BL Hylander… - Cancer Immunology …, 2014 - Springer
Long conserved mechanisms maintain homeostasis in living creatures in response to a
variety of stresses. However, continuous exposure to stress can result in unabated …

[HTML][HTML] Housing temperature-induced stress drives therapeutic resistance in murine tumour models through β2-adrenergic receptor activation

JWL Eng, CB Reed, KM Kokolus, R Pitoniak… - Nature …, 2015 - nature.com
Cancer research relies heavily on murine models for evaluating the anti-tumour efficacy of
therapies. Here we show that the sensitivity of several pancreatic tumour models to cytotoxic …

[HTML][HTML] Role of adrenergic receptor signalling in neuroimmune communication

S Chhatar, G Lal - Current Research in Immunology, 2021 - Elsevier
Neuroimmune communication plays a crucial role in maintaining homeostasis and promptly
responding to any foreign insults. Sympathetic nerve fibres are innervated into all the …

Molecular mechanisms underlying psychological stress and cancer

K Jin Shin, Y Jin Lee, Y Ryoul Yang… - Current …, 2016 - ingentaconnect.com
Psychological stress is an emotion experienced when people are under mental pressure or
encounter unexpected problems. Extreme or repetitive stress increases the risk of …

[HTML][HTML] The use of antihypertensive drugs as coadjuvant therapy in cancer

JA Carlos-Escalante, M de Jesus-Sanchez… - Frontiers in …, 2021 - frontiersin.org
Cancer is a complex group of diseases that constitute the second largest cause of mortality
worldwide. The development of new drugs for treating this disease is a long and costly …