Pathogenesis of Helicobacter pylori infection

V Camilo, T Sugiyama, E Touati - Helicobacter, 2017 - Wiley Online Library
Helicobacter pylori is responsible for the most commonly found infection in the world's
population. It is the major risk factor for gastric cancer development. Numerous studies …

Helicobacter pylori infection

J Cho, A Prashar, NL Jones… - Gastroenterology Clinics, 2021 - gastro.theclinics.com
Helicobacter pylori is a common pathogen that is responsible for much gastrointestinal
morbidity worldwide. The discovery of the organism and its eradication by combination …

Meddling with metal sensors: Fur-family proteins as signaling hubs

CH Steingard, JD Helmann - Journal of Bacteriology, 2023 - Am Soc Microbiol
The ferric uptake regulator (Fur) protein is the founding member of the FUR superfamily of
metalloregulatory proteins that control metal homeostasis in bacteria. FUR proteins regulate …

Ferric uptake regulator (Fur) reversibly binds a [2Fe-2S] cluster to sense intracellular iron homeostasis in Escherichia coli

CR Fontenot, H Tasnim, KA Valdes, CV Popescu… - Journal of Biological …, 2020 - ASBMB
The ferric uptake regulator (Fur) is a global transcription factor that regulates intracellular
iron homeostasis in bacteria. The current hypothesis states that when the intracellular" free" …

Critical assessment of interactions between ct-DNA and choline-based magnetic ionic liquids: evidences of compaction

KD Tulsiyan, SK Panda, MK Rana, HS Biswal - Chemical Science, 2024 - pubs.rsc.org
Ionic liquids (ILs) have become an alternative green solvent for storage and for stability of
DNA. However, an in-depth understanding of binding and molecular interactions between …

Recent Advances in the Siderophore Biology of Shewanella

L Liu, W Wang, S Wu, H Gao - Frontiers in Microbiology, 2022 - frontiersin.org
Despite the abundance of iron in nature, iron acquisition is a challenge for life in general
because the element mostly exists in the extremely insoluble ferric (Fe3+) form in oxic …

Delineation of the pH-responsive regulon controlled by the Helicobacter pylori ArsRS two-component system

JT Loh, MV Shum, SDR Jossart… - Infection and …, 2021 - Am Soc Microbiol
Helicobacter pylori encounters a wide range of pH within the human stomach. In a
comparison of H. pylori cultured in vitro under neutral or acidic conditions, about 15% of …

Acid-responsive activity of the Helicobacter pylori metalloregulator NikR

MD Jones, Y Li, DB Zamble - Proceedings of the National …, 2018 - National Acad Sciences
Helicobacter pylori is a human pathogen that infects the stomach, where it experiences
variable pH. To survive the acidic gastric conditions, H. pylori produces large quantities of …

Allosteric control of metal-responsive transcriptional regulators in bacteria

KA Baksh, DB Zamble - Journal of Biological Chemistry, 2020 - ASBMB
Many transition metals are essential trace nutrients for living organisms, but they are also
cytotoxic in high concentrations. Bacteria maintain the delicate balance between metal …

Insights into the Orchestration of Gene Transcription Regulators in Helicobacter pylori

A Vannini, D Roncarati, F D'Agostino… - International Journal of …, 2022 - mdpi.com
Bacterial pathogens employ a general strategy to overcome host defenses by coordinating
the virulence gene expression using dedicated regulatory systems that could raise intricate …