Replication protein A [RPA; also known as replication factor A (RFA) and human single-
stranded DNA-binding protein] is a single-stranded DNA-binding protein that is required for …

Stability and function of eukaryotic genomes are closely linked to chromatin structure and
organization. During cell division the entire genome must be accurately replicated and the …

Cyclin E was first identified by screening human cDNA libraries for genes that would
complement G1 cyclin mutations in Saccharomyces cerevisiae and has subsequently been …

The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the
remarkable progress in chromatin research over the past three years. It has been …

Cyclin A is particularly interesting among the cyclin family because it can activate two
different cyclin-dependent kinases (CDKs) and functions in both S phase and mitosis. An …

It has been proposed that the functions of the cyclin-dependent kinase inhibitors p21
Cip1/Waf1 and p27 Kip1 are limited to cell cycle control at the G 1/S-phase transition and in …

Skeletal muscle differentiation entails the coordination of muscle-specific gene expression
and terminal withdrawal from the cell cycle. This cell cycle arrest in the G0 phase requires …

DNA replication occurs in microscopically visible complexes at discrete sites (replication
foci) in the nucleus. These foci consist of DNA associated with replication machineries, ie …

Cell‐penetrating peptides (CPPs) are capable of introducing a wide range of cargoes into
living cells. Descriptions of the internalization process vary from energy‐independent cell …

The F-box protein p45 SKP2 is the substrate-targeting subunit of the ubiquitin–protein ligase
SCF SKP2 and is frequently overexpressed in transformed cells. Here we report that …