Background: Diseases with inflammatory etiopathology have increased in incidence in
recent times. Drugs used for therapeutic management of such inflammatory diseases are …

Flavones are natural phytochemicals broadly distributed in our diet. Their anti-inflammatory
properties provide unique opportunities to control the innate immune system and …

Pueraria tuberosa (Roxb. ex Willd.) DC.(Fabaceae), also known as Indian Kudzu (vidari
kand), is a perennial herb distributed throughout India and other Asian countries …

A metabolic bone disorder called osteoporosis is characterized by decreased bone mass
and compromised microarchitecture. This condition can deteriorate bones and raise the risk …

Background Chemotherapy drugs especially anthracyclines are widely used in the treatment
of hematological malignancies and solid tumors. However, their clinical application is limited …

Isoorientin is a natural C-glucosyl flavone that is generating a lot of interest due to its
multiple pharmacological activities. Increasing experimental data have shown that the robust …

Isoorientin (ISO) is a natural flavonoid, which is a 6-C-glucoside of luteolin, and has been
demonstrated to possess multiple biological properties. In this study, the effects of ISO on the …

Cisplatin (CDDP) is a widely used chemotherapeutic agent for various solid tumors, but its
severe side effects, particularly nephrotoxicity, limit its clinical application. Isoorientin (Iso) is …

Inflammation prevailing conditions delay healing processes of damaged tissues, leading to
a functional impairment. Although anti-inflammatory drugs are clinically available, they often …

Nephropathy can occur following exposure of the kidneys to oxidative stress. Oxidative
stress is the result of reactive oxygen species (ROS) formation due to intracellular …