Hox genes in vertebrate development

R Krumlauf - Cell, 1994 - Elsevier
Organization and Evolution of Hox/HOM-C Complexes The genomic structural and
organizational similarities between vertebrate Hox and Drosophila HOM-C complexes …

HP1 and the dynamics of heterochromatin maintenance

C Maison, G Almouzni - Nature reviews Molecular cell biology, 2004 - nature.com
Heterochromatin maintenance is crucial for the clonal inheritance of cell identity, to ensure
the proper segregation of chromosomes and the regulation of gene expression. Although it …

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP …

RA Frye - Biochemical and biophysical research communications, 1999 - Elsevier
The yeast Sir2 protein regulates epigenetic gene silencing and as a possible antiaging
effect it suppresses recombination of rDNA. Studies involving cobB, a bacterial SIR2-like …

HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

AR Strom, RJ Biggs, EJ Banigan, X Wang, K Chiu… - Elife, 2021 - elifesciences.org
Chromatin, which consists of DNA and associated proteins, contains genetic information and
is a mechanical component of the nucleus. Heterochromatic histone methylation controls …

The many lives of KATs—detectors, integrators and modulators of the cellular environment

BN Sheikh, A Akhtar - Nature Reviews Genetics, 2019 - nature.com
Research over the past three decades has firmly established lysine acetyltransferases
(KATs) as central players in regulating transcription. Recent advances in genomic …

The protein encoded by the Drosophila position‐effect variegation suppressor gene Su (var) 3‐9 combines domains of antagonistic regulators of homeotic gene …

B Tschiersch, A Hofmann, V Krauss, R Dorn… - The EMBO …, 1994 - embopress.org
Modifier mutations of position‐effect variegation (PEV) represent a useful tool for a genetic
and molecular dissection of genes connected with chromatin regulation in Drosophila. The …

The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

P Jeppesen, BM Turner - Cell, 1993 - cell.com
We have immunolabeled human and mouse metaphase chromosomes with antibodies
specific for the acetylated isoforms of histone H4. All chromosomes were labeled in regions …

[HTML][HTML] Functional mammalian homologues of the Drosophila PEV‐modifier Su (var) 3‐9 encode centromere‐associated proteins which complex with the …

L Aagaard, G Laible, P Selenko, M Schmid… - The EMBO …, 1999 - embopress.org
The chromo and SET domains are conserved sequence motifs present in chromosomal
proteins that function in epigenetic control of gene expression, presumably by modulating …

Characterization of the CHD family of proteins

T Woodage, MA Basrai, AD Baxevanis… - Proceedings of the …, 1997 - National Acad Sciences
The murine gene CHD1 (MmCHD1) was previously isolated in a search for proteins that
bound a DNA promoter element. The presence of chromo (chromatin organization modifier) …

Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1

Q Ye, HJ Worman - Journal of Biological Chemistry, 1996 - ASBMB
At the nuclear envelope in higher eukaryotic cells, the nuclear lamina and the
heterochromatin are adjacent to the inner nuclear membrane, and their attachment is …