In human demyelinating diseases such as multiple sclerosis (MS), an imbalance between
demyelination and remyelination can trigger progressive degenerative processes. The …

Multiple Sclerosis (MS) is a neuroinflammatory disorder, which is histopathologically
characterized by multifocal inflammatory demyelinating lesions affecting both the central …

Multiple Sclerosis (MS) is traditionally considered an autoimmune-mediated demyelinating
disease, the pathoetiology of which is unknown. However, the key question remains whether …

The complement system is implicated in synapse loss in the MS hippocampus, but the
functional consequences of synapse loss remain poorly understood. Here, in post-mortem …

Multiple Sclerosis (MS) is a demyelinating disease of the human central nervous system
having an unconfirmed pathoetiology. Although animal models are used to mimic the …

Our prior investigations have demonstrated the pivotal role of IL-33 in facilitating the
maturation of oligodendrocytes (OLs), prompting our interest in exploring its potential …

Multiple sclerosis (MS) is a demyelinating, autoimmune disease that affects a large number
of young adults. Novel therapies for MS are needed considering the efficiency and safety …

Multiple sclerosis is an autoimmune disease characterised by demyelination in the central
nervous system. The cuprizone-induced demyelination model is often used in mice to test …

A change in visual perception is a frequent early symptom of multiple sclerosis (MS), the
pathoaetiology of which remains unclear. Following a slow demyelination process caused …

Hericium erinaceus mycelium extract (HEM), containing erinacine A (HeA) and erinacine S
(HeS), has shown promise in promoting the differentiation of oligodendrocyte precursor cells …