Defective T-cell response in beige mutant mice

RK Saxena, QB Saxena, WH Adler - Nature, 1982 - nature.com
A role for T cells in immune surveillance has long been suggested1, but the lack of high
tumour incidence in T cell-deficient nude mice represented a challenge to this hypothesis …

Regulation of natural killer activity in vivo. II. The effect of alcohol consumption on human peripheral blood natural killer activity

QB Saxena, E Mezey, WH Adler - International Journal of …, 1980 - Wiley Online Library
Natural killer (NK) activity of human peripheral blood lymphocytes (HPBL) was studied in 32
alcoholics and 15 control subjects in a 4‐h chromium release assay using K562 tumor target …

Lectin-induced cytotoxic activity in spleen cells from young and old mice. Age-related changes in types of effector cells, lymphokine production and response.

RK Saxena, QB Saxena, WH Adler - Immunology, 1988 - ncbi.nlm.nih.gov
Abstract Concanavalin A (Con A)-induced cytotoxic activity, interferon (IFN) and interleukin-2
(IL-2) levels in cultures of spleen cells from young (2-3 months) and old (22-24 months) …

Interleukin-2-induced activation of natural killer activity in spleen cells from old and young mice.

RK Saxena, QB Saxena, WH Adler - Immunology, 1984 - ncbi.nlm.nih.gov
Generation of natural killer (NK) activity in response to a partially purified preparation of rat
interleukin-2 (IL-2) was compared in spleen cells derived from young (8-10 weeks old) and …

Effect of protein calorie malnutrition on the levels of natural and inducible cytotoxic activities in mouse spleen cells.

QB Saxena, RK Saxena, WH Adler - Immunology, 1984 - ncbi.nlm.nih.gov
Six-week-old C57B1/6 female mice were fed a normal (24% protein) or an isocaloric but
protein-deficient (4% protein) diet. At different time periods after the initiation of diets, basal …

Natural killer cell activity in patients with carcinoma of the larynx and hypopharynx

TPU Wustrow, HP Zenner - The Laryngoscope, 1985 - Wiley Online Library
Natural killer (NK) cells have recently gained much attention as potential effector cells in
antitumor and antiviral immune defense mechanisms. The role of NK cells in patients with …

Antibody‐induced augmentation of murine natural killer cell activity

MJ Brunda, RB Herberman… - International Journal of …, 1981 - Wiley Online Library
Antibodies reactive with effector cells were shown to augment the cytotoxicity of spleen cells
from athymic nude and euthymic mice. The addition of alloantibody to the assay or …

Modulation of natural cytotoxicity by alloantibodies: IV. A comparative study of the activation of mouse spleen cell cytotoxicity by anti H-2 antisera, interferon, and …

RK Saxena, WH Adler, AA Nordin - Cellular Immunology, 1981 - Elsevier
Comparisons were made between the characteristics of cytotoxicity activation in mouse
spleen cells, induced by specific anti-H-2 antiserum, interferon (IF), interferon inducer (poly …

Enhancement of human natural killer activity by the monoclonal Leu-11 antibodies

SE Egawa, T Abo, N Hiwatashi - Cellular immunology, 1987 - Elsevier
Abstract The Fc receptor for IgG on human natural killer (NK) cells can be identified by a
series of murine monoclonal antibodies. When these antibodies with IgG 1 isotype (eg, Leu …

Natural killer cells interaction with carbon nanoparticles

A Alam, RK Saxena - Natural Killer Cells, 2017 - books.google.com
The increased use of nanomaterials for biomedical purposes has warranted the need to
introspect their toxicological properties and assess their utility to human health, particularly …