Electrospun nanofiber scaffold for vascular tissue engineering

AP Rickel, X Deng, D Engebretson, Z Hong - Materials Science and …, 2021 - Elsevier
Due to the prevalence of cardiovascular diseases, there is a large need for small diameter
vascular grafts that cannot be fulfilled using autologous vessels. Although medium to large …

Bio-inspired hemocompatible surface modifications for biomedical applications

M Douglass, M Garren, R Devine, A Mondal… - Progress in materials …, 2022 - Elsevier
When blood first encounters the artificial surface of a medical device, a complex series of
biochemical reactions is triggered, potentially resulting in clinical complications such as …

Durable immunomodulatory nanofiber niche for the functional remodeling of cardiovascular tissue

Y Liu, L Wang, Z Liu, Y Kang, T Chen, C Xu, T Zhu - ACS nano, 2023 - ACS Publications
Functional remodeling and prolonged anti-inflammatory responses are both vital for
repairing damage in the cardiovascular system. Although these aspects have each been …

Single and multi-functional coating strategies for enhancing the biocompatibility and tissue integration of blood-contacting medical implants

M Badv, F Bayat, JI Weitz, TF Didar - Biomaterials, 2020 - Elsevier
Device-associated clot formation and poor tissue integration are ongoing problems with
permanent and temporary implantable medical devices. These complications lead to …

[HTML][HTML] Functionalization of in vivo tissue-engineered living biotubes enhance patency and endothelization without the requirement of systemic anticoagulant …

H Yan, Q Cheng, J Si, S Wang, Y Wan, X Kong… - Bioactive Materials, 2023 - Elsevier
Vascular regeneration and patency maintenance, without anticoagulant administration,
represent key developmental trends to enhance small-diameter vascular grafts (SDVG) …

Fabrication of heparinized bi-layered vascular graft with PCL/PU/gelatin co-electrospun and chitosan/silk fibroin/gelatin freeze-dried hydrogel for improved …

A Almasi-Jaf, A Shamloo, H Shaygani, S Seifi - International Journal of …, 2023 - Elsevier
Fabricating a biocompatible small-diameter vascular graft (< 6 mm) with mechanical
properties similar to the natural vein and adding good anti-thrombogenic, endothelialization …

In vivo performance of decellularized vascular grafts: a review article

CH Lin, K Hsia, H Ma, H Lee, JH Lu - International journal of molecular …, 2018 - mdpi.com
Due to poor vessel quality in patients with cardiovascular diseases, there has been an
increased demand for small-diameter tissue-engineered blood vessels that can be used as …

Covalent grafting of PEG and heparin improves biological performance of electrospun vascular grafts for carotid artery replacement

T Zhu, H Gu, H Zhang, H Wang, H Xia, X Mo, J Wu - Acta Biomaterialia, 2021 - Elsevier
Rapid endothelialization of small-diameter vascular grafts remains a significant challenge in
clinical practice. In addition, compliance mismatch causes intimal hyperplasia and finally …

Surface modification and endothelialization of polyurethane for vascular tissue engineering applications: a review

I Adipurnama, MC Yang, T Ciach… - Biomaterials …, 2017 - pubs.rsc.org
Cardiovascular implants, especially vascular grafts made of synthetic polymers, find wide
clinical applications in the treatment of cardiovascular diseases. However, cases of failure …

Review of polymeric biomimetic small-diameter vascular grafts to tackle intimal hyperplasia

R Zizhou, X Wang, S Houshyar - ACS omega, 2022 - ACS Publications
Small-diameter artificial vascular grafts (SDAVG) are used to bypass blood flow in arterial
occlusive diseases such as coronary heart or peripheral arterial disease. However, SDAVGs …