Remote ischaemic conditioning—a new paradigm of self-protection in the brain

DC Hess, RA Blauenfeldt, G Andersen… - Nature Reviews …, 2015 - nature.com
Remote ischaemic conditioning (RIC) triggers endogenous protective pathways in distant
organs such as the kidney, heart and brain, and represents an exciting new paradigm in …

Preconditioning in neuroprotection: from hypoxia to ischemia

S Li, A Hafeez, F Noorulla, X Geng, G Shao… - Progress in …, 2017 - Elsevier
Sublethal hypoxic or ischemic events can improve the tolerance of tissues, organs, and even
organisms from subsequent lethal injury caused by hypoxia or ischemia. This phenomenon …

Remote ischemic perconditioning as an adjunct therapy to thrombolysis in patients with acute ischemic stroke: a randomized trial

KD Hougaard, N Hjort, D Zeidler, L Sørensen… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Remote ischemic preconditioning is neuroprotective in models
of acute cerebral ischemia. We tested the effect of prehospital rPerC as an adjunct to …

Chronic remote ischaemic conditioning in patients with symptomatic intracranial atherosclerotic stenosis (the RICA trial): a multicentre, randomised, double-blind sham …

C Hou, J Lan, Y Lin, H Song, Y Wang, W Zhao… - The Lancet …, 2022 - thelancet.com
Background Intracranial atherosclerotic stenosis (ICAS) is one of the most common causes
of stroke worldwide, and it is associated with a high risk of recurrent stroke with currently …

Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance

RA Stetler, RK Leak, Y Gan, P Li, F Zhang, X Hu… - Progress in …, 2014 - Elsevier
Preconditioning is a phenomenon in which brief episodes of a sublethal insult induce robust
protection against subsequent lethal injuries. Preconditioning has been observed in multiple …

Remote ischemic conditioning: from bench to bedside

SY Lim, DJ Hausenloy - Frontiers in physiology, 2012 - frontiersin.org
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue
against the detrimental effects of acute ischemia-reperfusion injury (IRI). It describes an …

Safety and efficacy of remote ischemic postconditioning after thrombolysis in patients with stroke

J An, Y Cheng, Y Guo, M Wei, M Gong, Y Tang… - Neurology, 2020 - AAN Enterprises
Objective To determine the effect of remote ischemic postconditioning (RIPC) on patients
with acute ischemic stroke (AIS) undergoing IV thrombolysis (IVT). Methods A single-center …

Remote ischemic limb preconditioning after subarachnoid hemorrhage: a phase Ib study of safety and feasibility

S Koch, M Katsnelson, C Dong, M Perez-Pinzon - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Making a limb transiently ischemic has been shown to induce
ischemic tolerance in a distant organ. This phenomenon is known as remote ischemic limb …

Remote ischemic conditioning to protect against ischemia-reperfusion injury: a systematic review and meta-analysis

D Brevoord, P Kranke, M Kuijpers, N Weber… - 2012 - journals.plos.org
Background Remote ischemic conditioning is gaining interest as potential method to induce
resistance against ischemia reperfusion injury in a variety of clinical settings. We performed …

Ischaemic and hypoxic conditioning: potential for protection of vital organs

JD Sprick, RT Mallet, K Przyklenk… - Experimental …, 2019 - Wiley Online Library
New Findings What is the topic of this review? Remote ischaemic preconditioning (RIPC)
and hypoxic preconditioning as novel therapeutic approaches for cardiac and …