Persistent diabetic macular edema: Definition, incidence, biomarkers, and treatment methods

OA Sorour, ES Levine, CR Baumal, AG Elnahry… - Survey of …, 2023 - Elsevier
Intravitreal antivascular endothelial growth factor (anti-VEGF) treatment has drastically
improved the visual and anatomical outcomes in patients with diabetic macular edema …

[HTML][HTML] AI-based monitoring of retinal fluid in disease activity and under therapy

U Schmidt-Erfurth, GS Reiter, S Riedl… - Progress in retinal and …, 2022 - Elsevier
Retinal fluid as the major biomarker in exudative macular disease is accurately visualized by
high-resolution three-dimensional optical coherence tomography (OCT), which is used …

[HTML][HTML] Transfer learning for automated OCTA detection of diabetic retinopathy

D Le, M Alam, CK Yao, JI Lim, YT Hsieh… - … Vision Science & …, 2020 - tvst.arvojournals.org
Purpose: To test the feasibility of using deep learning for optical coherence tomography
angiography (OCTA) detection of diabetic retinopathy. Methods: A deep-learning …

Optimizing the OCTA layer fusion option for deep learning classification of diabetic retinopathy

B Ebrahimi, D Le, M Abtahi, AK Dadzie… - Biomedical Optics …, 2023 - opg.optica.org
The purpose of this study is to evaluate layer fusion options for deep learning classification
of optical coherence tomography (OCT) angiography (OCTA) images. A convolutional …

[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Ophthalmic imaging in diabetic retinopathy: A review

O Nanegrungsunk, D Patikulsila… - Clinical & Experimental …, 2022 - Wiley Online Library
Retinal imaging has been a key tool in the diagnosis, evaluation, management and
documentation of diabetic retinopathy (DR) and diabetic macular oedema (DMO) for many …

Quantitative optical coherence tomography angiography: a review

X Yao, MN Alam, D Le, D Toslak - Experimental biology and …, 2020 - journals.sagepub.com
As a new optical coherence tomography (OCT) modality, OCT angiography (OCTA) provides
a noninvasive method to detect microvascular distortions correlated with eye conditions. By …

Assessment of parafoveal diabetic macular ischemia on optical coherence tomography angiography images to predict diabetic retinal disease progression and visual …

D Yang, Z Tang, A Ran, TX Nguyen, S Szeto… - JAMA …, 2023 - jamanetwork.com
Importance The presence of diabetic macular ischemia (DMI) on optical coherence
tomography angiography (OCTA) images predicts diabetic retinal disease progression and …

[HTML][HTML] New insights in resistant diabetic macular edema

DAK Kuroiwa, FK Malerbi, CVS Regatieri - Ophthalmologica, 2021 - karger.com
Diabetic macular edema (DME) is the most common cause of vision loss in diabetic eyes,
and due to the rapid rise in the number of diabetic patients, the treatment burden has …

[HTML][HTML] Angiographic biomarkers are significant predictors of treatment response to intravitreal aflibercept in diabetic macular edema

M Hein, A Vukmirovic, IJ Constable, V Raja… - Scientific Reports, 2023 - nature.com
This prospective single-center study aims to identify biomarkers that predict improvement in
best-corrected visual acuity (BCVA) and central retinal thickness (CRT) at 6 months, in 76 …