Next generation gold drugs and probes: chemistry and biomedical applications

RT Mertens, S Gukathasan, AS Arojojoye… - Chemical …, 2023 - ACS Publications
The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Gold-catalyzed organic reactions

ASK Hashmi - Chemical reviews, 2007 - ACS Publications
Gold has accompanied mankind from the very early days; no name of a chemist is
associated with the discovery of the element gold. It is probably the only chemical element …

Advances in cobalt complexes as anticancer agents

CR Munteanu, K Suntharalingam - Dalton Transactions, 2015 - pubs.rsc.org
The evolution of resistance to traditional platinum-based anticancer drugs has compelled
researchers to investigate the cytostatic properties of alternative transition metal-based …

Gold-based medicine: a paradigm shift in anti-cancer therapy?

CI Yeo, KK Ooi, ERT Tiekink - Molecules, 2018 - mdpi.com
A new era of metal-based drugs started in the 1960s, heralded by the discovery of potent
platinum-based complexes, commencing with cisplatin [(H3N) 2PtCl2], which are effective …

Anticancer activity of metal complexes: involvement of redox processes

U Jungwirth, CR Kowol, BK Keppler, CG Hartinger… - 2011 - liebertpub.com
Cells require tight regulation of the intracellular redox balance and consequently of reactive
oxygen species for proper redox signaling and maintenance of metal (eg, of iron and …

Selected organophosphorus compounds with biological activity. Applications in medicine

S Demkowicz, J Rachon, M Daśko, W Kozak - RSC advances, 2016 - pubs.rsc.org
The purpose of this article is to provide an overview of the latest applications of
organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs …

Gold nanomaterials as key suppliers in biological and chemical sensing, catalysis, and medicine

M Falahati, F Attar, M Sharifi, AA Saboury… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Abstract Background Gold nanoparticles (AuNPs) with unique physicochemical properties
have received a great deal of interest in the field of biological, chemical and biomedical …

Copper binding agents acting as copper ionophores lead to caspase inhibition and paraptotic cell death in human cancer cells

S Tardito, I Bassanetti, C Bignardi, L Elviri… - Journal of the …, 2011 - ACS Publications
We report a quantitative structure− activity relationship study of a new class of pyrazole-
pyridine copper complexes that establishes a clear correlation between the ability to …

Bioinorganic chemistry of titanium

KM Buettner, AM Valentine - Chemical Reviews, 2012 - ACS Publications
Louis-Camille Maillard is best remembered for his namesake organic reaction, one between
an amino acid and a reducing sugar. 1 In his final four papers before his death in 1936 …

Developing vanadium as an antidiabetic or anticancer drug: A clinical and historical perspective

DC Crans, L Henry, G Cardiff, BI Posner - Met. Ions Life Sci, 2019 - degruyter.com
Vanadium has been known for centuries to have beneficial effects on health and has the
potential to be used as an alternative to other diabetic and anticancer medicines. The …