Perspectives on the Role of Isoliquiritigenin in Cancer

KL Wang, YC Yu, SM Hsia - Cancers, 2021 - mdpi.com
Simple Summary Isoliquiritigenin (ISL), a natural bioactive compound with a chalcone
structure, demonstrates high antitumor efficacy. This review presents a summary of the latest …

Macrophage-based nanotherapeutic strategies in ulcerative colitis

J Zhang, Y Zhao, T Hou, H Zeng, D Kalambhe… - Journal of controlled …, 2020 - Elsevier
Macrophages, an important component of the innate immune response, are a key regulator
of intestinal microenvironment homeostasis. These cells essentially contribute to chronic …

Maresin 1 alleviates dextran sulfate sodium-induced ulcerative colitis by regulating NRF2 and TLR4/NF-kB signaling pathway

S Qiu, P Li, H Zhao, X Li - International immunopharmacology, 2020 - Elsevier
Objective Ulcerative colitis (UC) is one of the most common gastrointestinal diseases,
characterized as a chronic, relapsing inflammation that causes damage to the colonic …

[HTML][HTML] The role and mechanism of flavonoid herbal natural products in ulcerative colitis

JC Xue, S Yuan, H Meng, XT Hou, J Li… - Biomedicine & …, 2023 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine that presents
clinically with abdominal pain, mucopurulent stools, and posterior urgency. The lesions of …

[HTML][HTML] Lactoferrin-mediated macrophage targeting delivery and patchouli alcohol-based therapeutic strategy for inflammatory bowel diseases

Y Zhao, Y Yang, J Zhang, R Wang, B Cheng… - … Pharmaceutica Sinica B, 2020 - Elsevier
Inflammatory bowel diseases (IBD) are the incurable chronic recurrent gastrointestinal
disorders and currently lack in safe and effective drugs. In this study, patchouli alcohol, a …

Anneslea fragrans Wall. ameliorates ulcerative colitis via inhibiting NF-κB and MAPK activation and mediating intestinal barrier integrity

X Deng, Y Wang, L Tian, M Yang, S He, Y Liu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Anneslea fragrans Wall. is traditionally used as a
folk medicine in treating indigestion, fever, dysentery, diarrhea, and liver inflammation in …

Total Flavonoids of Glycyrrhiza uralensis Alleviates Irinotecan-Induced Colitis via Modification of Gut Microbiota and Fecal Metabolism

SJ Yue, YF Qin, A Kang, HJ Tao, GS Zhou… - Frontiers in …, 2021 - frontiersin.org
Irinotecan (CPT-11)-induced gastrointestinal toxicity strongly limits its anticancer efficacy.
Glycyrrhiza uralensis Fisch., especially flavonoids, has strong anti-inflammatory and …

Pharmacological effects and underlying mechanisms of licorice‐derived flavonoids

Y Wu, Z Wang, Q Du, Z Zhu, T Chen… - Evidence‐Based …, 2022 - Wiley Online Library
Glycyrrhizae Radix et Rhizoma is the most frequently prescribed natural medicine in China
and has been used for more than 2,000 years. The flavonoids of licorice have garnered …

Natural products modulate NLRP3 in ulcerative colitis

JC Xue, S Yuan, XT Hou, H Meng, BH Liu… - Frontiers in …, 2023 - frontiersin.org
Ulcerative colitis (UC) is a clinically common, progressive, devastating, chronic inflammatory
disease of the intestine that is recurrent and difficult to treat. Nod-like receptor protein 3 …

Natural chalcones in Chinese materia medica: Licorice

D Wang, J Liang, J Zhang, Y Wang… - … and Alternative Medicine, 2020 - Wiley Online Library
Licorice is an important Chinese materia medica frequently used in clinical practice, which
contains more than 20 triterpenoids and 300 flavonoids. Chalcone, one of the major classes …