Olea europaea L. fruit is a peculiar vegetal matrix containing high levels of fatty acids (98–
99% of the total weight of extra-virgin olive oil, EVOO) and low quantities (1–2%) of …

Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

Endothelial cells (ECs) are sentinels of cardiovascular health. Their function is reduced by
the presence of cardiovascular risk factors, and is regained once pathological stimuli are …

Advancing age is the major risk factor for the development of CVD (cardiovascular
diseases). This is attributable, in part, to the development of vascular endothelial …

The vascular endothelium regulates blood flow in response to physiological needs.
Endothelial dysfunction is closely related to atherosclerosis and its risk factors, and it …

Background: Statins have long been used for the protection against coronary artery disease
(CAD). Their beneficial effect apart from cholesterol reduction lies in their pleiotropic …

Rationale: Through localized delivery of rapamycin via a biomimetic drug delivery system, it
is possible to reduce vascular inflammation and thus the progression of vascular disease …

Perivascular adipose tissue (PVAT), the adipose tissue that surrounds most of the
vasculature, has emerged as an active component of the blood vessel wall regulating …

Adipose-derived mesenchymal stem/stromal cells (ASCs) are an adult stem cell population
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …

Objective To determine if hyperuricemia and gouty arthritis are independent risk factors for
acute myocardial infarction (MI) and, if so, whether they are independent of renal function …