The CD57 antigen (alternatively HNK-1, LEU-7, or L2) is routinely used to identify terminally
differentiated 'senescent'cells with reduced proliferative capacity and altered functional …

Highlights•NK cells can kill virus-infected cells and protect against severe infections.•Long-
lived memory NK cells may develop after vaccination or infection.•NK cells are potent …

NK cells play a key role in immune response against HIV infection. These cells can destroy
infected cells and contribute to adequate and strong adaptive immune responses, by acting …

The persistence of virally infected cells as reservoirs despite effective antiretroviral therapy is
a major barrier to an HIV/SIV cure. These reservoirs are predominately contained within …

Natural killer (NK) cells are the first line of defense against pathogens of the immune system
and also play an important role in resistance against HIV. The activating receptor NKG2C …

Despite being under constant exposure to HIV-1, some individuals do not show serological
or clinical evidence of infection and are known as HESN (HIV-Exposed Seronegative) …

Immunotherapy, via intra-vesical instillations of BCG, is the therapy of choice for patients
with high-risk non-muscle invasive bladder cancer. The subsequent recruitment of …

Atopic dermatitis (AD) is a complex, multifactorial skin disease, characterized by pruritus and
predominant Th2 inflammation. Innate immune cells may play a role in AD development and …

Some individuals are resistant to HIV-1 infection despite repeated exposure to the virus,
suggesting the presence of a complex antiviral response. Innate factors like IL-22 exert gut …

Background Chronic HIV infection is known to trigger a population redistribution and
alteration in the functional capacity of natural killer (NK) cells. Because of improved …