Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …

Cancer is a disease that seriously threatens human health. Based on the improvement of
traditional treatment methods and the development of new treatment modes, the pattern of …

Nanoparticle-based drug delivery system offers a promising platform for combination cancer
therapy. However, the inefficient drug release in cells reduces the therapeutic efficacy of …

Previous studies have shown that chemotherapeutic efficacy could be enhanced with
targeted drug delivery. Various DNA origami nanostructures have been investigated as drug …

Lung malignancies accounted for 11% of cancers worldwide in 2020 and remained the
leading cause of cancer deaths. About 80% of lung cancers belong to non-small cell lung …

Heterogeneity and drug resistance of tumor cells are the leading causes of incurability and
poor survival for patients with recurrent breast cancer. In order to accurately deliver the …

Cell-penetrating peptides (CPPs) are promising vehicles for intracellular delivery of different
cargoes. Although various CPPs are designed for targeted delivery of nanomedicines and …

Background: The development of modern nanomedicine greatly depends on the
involvement of novel materials as drug delivery system. In order to maximize the therapeutic …

The treatment of various large bone defects has remained a challenge for orthopedic
surgeons for a long time. Recent research indicates that curculigoside (CUR) extracted from …

Cell-based assays are important for drug development. Among these, the cell viability assay
damages the cells due to the use of toxic reagents, is time-consuming, and has multi-step …