Stroke remains a leading cause of adult disability and the demand for stroke rehabilitation
services is growing. Substantial advances are yet to be made in stroke rehabilitation practice …

Environmental enrichment (EE) has been widely used as a means to enhance brain
plasticity mechanisms (eg, increased dendritic branching, synaptogenesis, etc.) and improve …

A major goal of the Stroke Recovery and Rehabilitation Roundtable (SRRR) is to accelerate
development of effective treatments to enhance stroke recovery beyond that expected to …

Dose articulation is a universal issue of intervention development and testing. In stroke
recovery, dose of a nonpharmaceutical intervention appears to influence outcome but is …

The 2 classes of drugs that have been most investigated as stroke recovery treatments to
date are serotonergic and dopaminergic. Building on prior smaller studies, the FLAME study …

Stroke results in local neural disconnection and brain-wide neuronal network dysfunction
leading to neurological deficits. Beyond the hyper-acute phase of ischaemic stroke, there is …

Introduction: High doses of activity-based rehabilitation therapy improve outcomes after
stroke, but many patients do not receive this for various reasons such as poor access …

Background Environmental enrichment involves organization of the environment and
provision of equipment to facilitate engagement in physical, cognitive, and social activities …

Autophagy is crucial for maintaining cellular homeostasis, and can be activated after
ischemic stroke. It also participates in nerve injury and repair. The purpose of this study was …

Abstract Purpose of Review Studies in humans and animal models show that most recovery
from impairment occurs in the first 1–3 months after stroke as a result of both spontaneous …