Chronic pain is a major socioeconomic burden globally. The most frequent origin of chronic
pain is musculoskeletal. In inflammatory musculoskeletal diseases such as rheumatoid …

RA is a chronic, systemic, autoimmune disease characterized by inflammation and
degradation of the joints, causing significant negative impact on quality of life. In addition to …

Introduction Increasing evidence indicates that features suggestive of neuropathic pain may
also be present in patients with common rheumatic conditions. The objective of this study …

Chronic inflammatory pain is a severe clinical problem that greatly affects patients' quality of
life and causes huge economic burden. Microglia-mediated neuroinflammation exerts …

Background Pain is reported as the leading cause of disability in the common forms of
inflammatory arthritis conditions. Acting as a key player in nociceptive processing …

Background Pain remains a prevalent symptom for rheumatoid arthritis (RA) patients despite
a wide therapeutic choice. The objective of this study was to provide a multidimensional …

Objective To investigate the frequency of remaining pain in early rheumatoid arthritis (RA)
after 3 months of treatment with methotrexate as the only disease modifying antirheumatic …

Objective Many patients with rheumatoid arthritis (RA) report pain despite excellent control
of inflammation with immunotherapies. Variable degrees of coexisting fibromyalgia (FM) …

Pain is a major and common symptom reported as a top priority in patients with rheumatoid
arthritis (RA). Intuitively, RA-related pain is often considered to be a natural consequence of …

Background Treatment of chronic inflammatory pain remains a major goal in the clinic. It is
thus of prime importance to characterize inherent pathophysiological pathways to design …