Cancer of unknown primary site

N Pavlidis, G Pentheroudakis - The Lancet, 2012 - thelancet.com
Cancer of unknown primary site (CUP) is a well recognised clinical disorder, accounting for
3–5% of all malignant epithelial tumours. CUP is clinically characterised as an aggressive …

Contemporary management of lymph node metastases from an unknown primary to the neck: I. A review of diagnostic approaches

P Strojan, A Ferlito, JE Medina, JA Woolgar… - Head & …, 2013 - Wiley Online Library
In an era of advanced diagnostics, metastasis to cervical lymph nodes from an occult
primary tumor is a rare clinical entity and accounts for approximately 3% of head and neck …

Diagnosis and management of squamous cell carcinoma of unknown primary in the head and neck: ASCO guideline

E Maghami, N Ismaila, A Alvarez… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To provide evidence-based recommendations to practicing physicians and other
health care providers on the diagnosis and management of squamous cell carcinoma of …

[HTML][HTML] A mini review on cancer of unknown primary site: a clinical puzzle for the oncologists

N Pavlidis, H Khaled, R Gaafar - Journal of advanced research, 2015 - Elsevier
Cancer of unknown primary (CUP) is a well recognized clinical syndrome, accounting for 3–
5% of all malignancies. It is characterized as a disease with an early dissemination of …

A new paradigm for the diagnosis and management of unknown primary tumors of the head and neck: a role for transoral robotic surgery

V Mehta, P Johnson, A Tassler, S Kim… - The …, 2013 - Wiley Online Library
Abstract Objectives/Hypothesis: In 2% to 3% of patients with cancer metastatic to cervical
lymph nodes, a primary tumor will not be found despite exhaustive diagnostic efforts. The …

Cancers of unknown primary origin: current perspectives and future therapeutic strategies

GM Stella, R Senetta, A Cassenti, M Ronco… - Journal of translational …, 2012 - Springer
It is widely accepted that systemic neoplastic spread is a late event in tumour progression.
However, sometimes, rapidly invasive cancers are diagnosed because of appearance of …

The role of transoral robotic surgery, transoral laser microsurgery, and lingual tonsillectomy in the identification of head and neck squamous cell carcinoma of …

TS Fu, A Foreman, DP Goldstein… - … -Head & Neck …, 2016 - journals.sagepub.com
Background Squamous cell carcinoma of the head and neck can present as a cervical
metastasis from an unknown primary site. Recently, transoral robotic surgery (TORS) and …

Comprehensive management of HPV‐related squamous cell carcinoma of the head and neck of unknown primary

E Rassy, P Nicolai, N Pavlidis - Head & Neck, 2019 - Wiley Online Library
Background Human papillomavirus (HPV)‐related squamous cell carcinoma of unknown
primary (SCCUP) is currently rising in incidence but lacks a validated management …

[18F]FDG PET/MRI vs. PET/CT for whole-body staging in patients with recurrent malignancies of the female pelvis: initial results

K Beiderwellen, J Grueneisen, V Ruhlmann… - European journal of …, 2015 - Springer
Purpose To evaluate the diagnostic potential of PET/MRI with [18 F] FDG in recurrent
ovarian and cervical cancer in comparison to PET/CT. Methods A group of 19 patients with …

Diagnosis and management of metastatic neoplasms with unknown primary

T Bochtler, H Löffler, A Krämer - Seminars in diagnostic pathology, 2018 - Elsevier
In cancer of unknown primary (CUP), metastases are clinically and histologically confirmed,
but the primary tumor site remains elusive after extensive work-up. CUPs make up for 2–3 …