Mitochondria are highly dynamic organelles that participate in ATP generation and involve
calcium homeostasis, oxidative stress response, and apoptosis. Dysfunctional or damaged …

Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …

Vascular endothelial cells (VECs), which are lined up in the inner surface of blood vessels,
are in direct contact with the metabolite-related endogenous danger signals in the …

Atherosclerosis is a multifactorial chronic inflammatory disease of the arterial wall, and an
important pathological basis of coronary heart disease. Endothelial cells, vascular smooth …

Different blood flow patterns in the arteries can alter the adaptive phenotype of vascular
endothelial cells (ECs), thereby affecting the functions of ECs and are directly associated …

Background: Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors (i) are a class
of lipid-lowering drugs suggested to hold a plethora of beneficial effects independent of their …

Each cell is equipped with a conserved housekeeping mechanism, known as autophagy, to
recycle exhausted materials and dispose of injured organelles via lysosomal degradation …

The solid tumor microenvironment possesses a hypoxic condition, which promotes
aggressiveness and resistance to therapies. Hypoxic tumor cells undergo broadly metabolic …

Atherosclerosis is a chronic inflammatory vascular disease and a leading cause of death
worldwide. Macrophages play an important role in inflammatory responses, cell–cell …

Atherosclerosis is a progressive inflammatory disorder of the arterial vessel wall
characterized by substantial infiltration of macrophages, which exert both favourable and …