[HTML][HTML] Deregulation of HLA-I in cancer and its central importance for immunotherapy
It is now well accepted that many tumors undergo a process of clonal selection which means
that tumor antigens arising at various stages of tumor progression are likely to be …
that tumor antigens arising at various stages of tumor progression are likely to be …
NK cell recognition
LL Lanier - Annu. Rev. Immunol., 2005 - annualreviews.org
NK CELL RECOGNITION | Annual Reviews Menu Publications AZ Journal Information About
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Uterine natural killer cells: from foe to friend in reproduction
I Díaz-Hernández, D Alecsandru… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Recurrent miscarriage and pre-eclampsia are common reproductive
disorders, but their causes are often unknown. Recent evidence has provided new insight …
disorders, but their causes are often unknown. Recent evidence has provided new insight …
Human leukocyte antigen (HLA) and immune regulation: how do classical and non-classical HLA alleles modulate immune response to human immunodeficiency …
NB Crux, S Elahi - Frontiers in immunology, 2017 - frontiersin.org
The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …
involve a sophisticated array of immune response. These genetic elements may modulate …
Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1
WF Garcia-Beltran, A Hölzemer, G Martrus… - Nature …, 2016 - nature.com
The activating natural killer (NK)-cell receptor KIR3DS1 has been linked to the outcome of
various human diseases, including delayed progression of disease caused by human …
various human diseases, including delayed progression of disease caused by human …
Inhibitory leukocyte immunoglobulin-like receptors: Immune checkpoint proteins and tumor sustaining factors
Inhibitory leukocyte immunoglobulin-like receptors (LILRBs 1-5) transduce signals via
intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that recruit protein …
intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that recruit protein …
Role of human leukocyte antigen system as a predictive biomarker for checkpoint-based immunotherapy in cancer patients
Recent advances in cancer immunotherapy have clearly shown that checkpoint-based
immunotherapy is effective in a small subgroup of cancer patients. However, no effective …
immunotherapy is effective in a small subgroup of cancer patients. However, no effective …
Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition
A Ishitani, N Sageshima, N Lee… - The Journal of …, 2003 - journals.aai.org
In this study we focused on the structure and expression of the HLA-E, F, and G class I
complexes in placental tissue. Structural analysis included an examination of the peptides …
complexes in placental tissue. Structural analysis included an examination of the peptides …
Definitive class I human leukocyte antigen expression in gestational placentation: HLA‐F, HLA‐E, HLA‐C, and HLA‐G in extravillous trophoblast invasion on …
R Hackmon, L Pinnaduwage, J Zhang… - American journal of …, 2017 - Wiley Online Library
Problem The extravillous trophoblasts (EVT) express HLA‐C and HLA‐G, but HLA‐E and
HLA‐F are the subject of conflicting reports. In this study, we define the HLA expression …
HLA‐F are the subject of conflicting reports. In this study, we define the HLA expression …
Genetic and functional relationships between MHC and NK receptor genes
J Trowsdale - Immunity, 2001 - cell.com
Abstract HLA class I and NK receptors are encoded within dense clusters of immune loci.
The MHC, at 6p21. 3, and the complex containing the KIR loci, at 19q13. 4, both feature …
The MHC, at 6p21. 3, and the complex containing the KIR loci, at 19q13. 4, both feature …