[HTML][HTML] Nanoformulations of ursolic acid: a modern natural anticancer molecule

L Wang, Q Yin, C Liu, Y Tang, C Sun… - Frontiers in …, 2021 - frontiersin.org
Background: Ursolic acid (UA) is a natural pentacyclic triterpene derived from fruit, herb, and
other plants. UA can act on molecular targets of various signaling pathways, inhibit the …

Natural products containing the nitrile functional group and their biological activities

C Scotti, JW Barlow - Natural Product Communications, 2022 - journals.sagepub.com
The importance of nitriles as a key class of chemicals with applications across the sciences
is widely appreciated. The natural world is an underappreciated source of chemically …

Multiple QSAR and molecular modelling for identification of potent human adenovirus inhibitors

SN Mali, A Pandey - Journal of the Indian Chemical Society, 2021 - Elsevier
This study has investigated docking-based 2D-and 3D-quantitative structure-activity
relationships (QSARs) for a range of 53 hydroxybenzamide analogues as anti-Human …

[HTML][HTML] Drug resistance reversal potential of multifunctional thieno [3, 2-c] pyran via potentiation of antibiotics in MDR P. aeruginosa

GR Dwivedi, R Rai, R Pratap, K Singh, S Pati… - Biomedicine & …, 2021 - Elsevier
We explored the antibacterial potential (alone and combination) against multidrug resistant
(MDR) Pseudomonas aeruginosa isolates KG-P2 using synthesized thieno [3, 2-c] pyran-2 …

Design, synthesis, biological evaluation and molecular docking study of novel hybrid of pyrazole and benzimidazoles

NC Desai, DD Pandya, DJ Jadeja, SK Panda… - Chemical Data …, 2021 - Elsevier
The emergence of microbial resistance calls for an urgent need to synthesize new
antimicrobial agents which are more effective than currently available in the market. To …

Antibiotic Potentiation Through Phytochemical-Based Efflux Pump Inhibitors to Combat Multidrug Resistance Bacteria

HS Cheema, A Maurya, S Kumar… - Medicinal …, 2024 - ingentaconnect.com
Background: Antimicrobial resistance development poses a significant danger to the efficacy
of antibiotics, which were once believed to be the most efficient method for treating infections …

Survival and Genome Evolution Signatures of Klebsiella pneumoniae Isolates Originated in Seven Species of Aquatic Animals

H Guan, L Xie, L Chen - Diversity, 2023 - mdpi.com
Klebsiella pneumoniae can cause life-threatening pneumonia in humans. The bacterium is
also the causative agent of nosocomial infection diseases. In our recent research, we …

Synergy Potential of Ursolic Acid-Based Hybrid Molecules

KN Mishra, S Singh, HC Upadhyay… - Letters in Drug …, 2023 - ingentaconnect.com
Background: Ursolic acid (UA, 3β-hydroxy-urs-12-en-28-oic acid), a pentacyclic triterpenoid
from various medicinal plants, has been blessed with proven biological effects, including …

Design, synthesis and drug resistance reversal potential of novel curcumin mimics Van D: synergy potential of curcumin mimics

GR Dwivedi, S Khwaja, AS Negi, SS Panda… - Bioorganic …, 2021 - Elsevier
Being crucial part of plant-based novel discovery of drug from natural resources, a study was
done to explore the antibacterial potential of curcumin mimics in combination with antibiotics …

Herbal bioenhancers in microparticulate drug delivery

S Agrawal, P Gurjar, A Agarwal - Drug Deliv Technol Herb …, 2022 - degruyter.com
Review of microparticulate drug delivery unveils the boons that the system has to offer, yet
only minimal knowledge of the role of herbal bioenhancers is available. Scientists focus …