Importance A considerable number of clinical trials of neoadjuvant immunotherapy for
patients with resectable esophageal cancer are emerging. However, systematic evaluations …

Importance Surgery plays a critical role in the management of all stages of gastric cancer.
Observations For patients with early gastric cancer and low risk of lymph node metastasis …

Platinum-based chemotherapy is the standard first-line treatment for advanced esophageal
squamous cell carcinoma (ESCC). In this phase 3 study (ClinicalTrial. gov: NCT03829969) …

Objective To evaluate sintilimab versus placebo in combination with chemotherapy (cisplatin
plus paclitaxel or cisplatin plus 5-fluorouracil) as first line treatment of unresectable locally …

PURPOSE Patients with advanced esophageal cancer have a poor prognosis and limited
treatment options after first-line chemotherapy. PATIENTS AND METHODS In this open …

Background Camrelizumab and chemotherapy demonstrated durable antitumor activity with
a manageable safety profile as first-line treatment in patients with advanced esophageal …

Background To investigate the safety and activity of preoperative pembrolizumab combined
with chemoradiotherapy for resectable oesophageal squamous cell carcinoma …

In the current era of precision medicine, the identification of genomic alterations has
revolutionised the management of patients with solid tumours. Recent advances in the …

Cancer is one of the foremost health problems worldwide and is among the leading causes
of death in the United States. Gastrointestinal tract cancers account for almost one third of …

Although surgery was the standard treatment for early gastrointestinal cancers, endoscopic
resection is now a standard treatment for early gastrointestinal cancers without regional …