The ability to form biofilms is a crucial virulence trait for several microorganisms, including
Klebsiella pneumoniae–a Gram-negative encapsulated bacterium often associated with …

Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Animal models have been developed to study the complex cellular and biochemical
processes of wound repair and to evaluate the efficacy and safety of potential therapeutic …

Delayed wound healing can cause significant issues for immobile and ageing individuals as
well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and …

Background: Despite a growing consensus that biofilms contribute to a delay in the healing
of chronic wounds, conflicting evidence pertaining to their identification and management …

Pseudomonas aeruginosa is a ubiquitous organism that is the focus of intense research
because of its prominent role in disease. Due to its relatively large genome and flexible …

The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …

Significance: Microorganisms can exist both in the planktonic and biofilm state. Each
phenotypic state has a role to play in delaying healing and causing infections of both acute …

Significance: The incidence, cost, morbidity, and mortality associated with non-healing of
chronic skin wounds are dramatic. With the increasing numbers of people with obesity …

Wound infection is a complex pathology that may manifest either as a rapid onset acute
condition, or as a prolonged chronic condition. Although systemic antibiotic therapy is often …