U0126: Not only a MAPK kinase inhibitor

Y You, Y Niu, J Zhang, S Huang, P Ding… - Frontiers in …, 2022 - frontiersin.org
U0126, as an inhibitor of the MAPK signaling pathway, is closely related to various
biological processes, such as differentiation, cell growth, autophagy, apoptosis, and stress …

ANGPTL 2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis

H Horiguchi, M Endo, K Kawane, T Kadomatsu… - The EMBO …, 2017 - embopress.org
The intestinal epithelium continually self‐renews and can rapidly regenerate after damage.
Dysregulation of intestinal epithelial homeostasis leads to severe inflammatory bowel …

miR-217 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by binding to Runx2

YL Zhu, S Wang, DG Ding, L Xu… - Molecular medicine …, 2017 - spandidos-publications.com
The elucidation of the underlying molecular mechanisms regulating the osteogenic
differentiation of bone marrow-derived mesenchymal stem cells (BMSCs) is of great …

Regulation of adipogenesis through differential modulation of ROS and kinase signaling pathways by 3, 4′‐dihydroxyflavone treatment

J Han, HY Choi, AA Dayem, K Kim… - Journal of Cellular …, 2017 - Wiley Online Library
Studies on adipogenesis may be important for regulating human and/or animal obesity,
which causes several complications such as, type II diabetes, hypertension, and …

[HTML][HTML] Icariin stimulates differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs) through activation of cAMP/PKA/CREB

D Lou, J Ye, L Yang, Z Wu, W Zheng… - Brazilian Journal of …, 2019 - SciELO Brasil
Icariin, a prenylated flavonol glycoside isolated from Epimedium, has been considered as a
potential alternative therapy for osteoporosis. The present study aimed to clarify the detailed …

Bioactive surface modification of polycaprolactone using MG63-conditioned medium can induce osteogenic differentiation of mesenchymal stem cells

CH Lin, MC Chang, SC Hung, SY Lee… - Journal of Materials …, 2017 - Springer
We demonstrated an approach that modifies the scaffold surface with a range of molecules,
simultaneously conjugated to the scaffold by a single treatment with concentrated …

[HTML][HTML] Modulation of osteogenic differentiation of adipose-derived stromal cells by co-treatment with 3, 4'-dihydroxyflavone, U0126, and n-acetyl cysteine

K Song, GM Yang, J Han, M Gil… - … Journal of Stem …, 2022 - synapse.koreamed.org
Methods and Results Treatment of 3, 4'-DHF led to increased osteogenic differentiation of
eADSCs by increasing phosphorylation of ERK and modulating Reactive Oxygen Species …

[HTML][HTML] Bone marrow mesenchymal stem cells differentiate into intestinal epithelioid cells through the ERK1/2 pathway

T Jiang, M Shi, G Xia, Y Yang, J Xu, Y Lei… - The Turkish Journal …, 2020 - ncbi.nlm.nih.gov
Materials and Methods rBMSCs were isolated from rat femurs and tibias. Differentiation was
induced by co-culturing rBMSCs with rat intestinal epithelial cells (mIEC-6) using Transwell …

Signal proteins involved in myogenic stem cells differentiation

Z Huang, X Wang, D Chen - Current Protein and Peptide …, 2017 - ingentaconnect.com
Myogenic stem cells are composed of satellite cells, multipotential muscle-derived stem cells
and bone-marrow mesenchymal stem cells. They are multipotential stem cells that can …

Inhibition of ERK1/2 downregulates triglyceride and palmitic acid accumulation in cashmere goat foetal fibroblasts

X Feng, L Bao, M Wu, D Zhang, L Yao… - Journal of Applied …, 2018 - Taylor & Francis
An extracellular signal-regulated kinase (ERK) is a mitogen-activated protein kinase (MAPK)
in mammalian cells that interact with the mechanistic target of rapamycin (mTOR) signalling …