Systemic lupus erythematosus in children and adolescents

DM Levy, S Kamphuis - Pediatric Clinics, 2012 - pediatric.theclinics.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can involve any
organ system, and may lead to significant morbidity and even mortality. This article reviews …

Pediatric lupus—are there differences in presentation, genetics, response to therapy, and damage accrual compared with adult lupus?

R Mina, HI Brunner - Rheumatic Disease Clinics, 2010 - rheumatic.theclinics.com
An estimated 10% to 20% of patients experience the onset of systemic lupus erythematosus
(SLE) before adulthood. More precise estimates are difficult due to a lack of a clear age limit …

Collagen (COL4A) mutations are the most frequent mutations underlying adult focal segmental glomerulosclerosis

C Gast, RJ Pengelly, M Lyon, DJ Bunyan… - Nephrology Dialysis …, 2016 - academic.oup.com
Background Multiple genes underlying focal segmental glomerulosclerosis (FSGS) and/or
steroid-resistant nephrotic syndrome (SRNS) have been identified, with the recent inclusion …

The Italian Society for Pediatric Nephrology (SINePe) consensus document on the management of nephrotic syndrome in children: Part I-Diagnosis and treatment of …

A Pasini, E Benetti, G Conti, L Ghio, M Lepore… - Italian journal of …, 2017 - Springer
This consensus document is aimed at providing an updated, multidisciplinary overview on
the diagnosis and treatment of pediatric nephrotic syndrome (NS) at first presentation. It is …

Update on differences between childhood-onset and adult-onset systemic lupus erythematosus

R Mina, HI Brunner - Arthritis research & therapy, 2013 - Springer
Systemic lupus erythematosus (SLE) is a complex autoimmune disease and occurs
worldwide in both children and adults. The estimated annual incidence among children is …

The role of complement in organ transplantation

M Grafals, JM Thurman - Frontiers in immunology, 2019 - frontiersin.org
The current immunosuppressive protocols used in transplant recipients have improved short-
term outcomes, but long-term allograft failure remains an important clinical problem. Greater …

Initial steroid sensitivity in children with steroid-resistant nephrotic syndrome predicts post-transplant recurrence

WY Ding, A Koziell, HJ McCarthy… - Journal of the …, 2014 - journals.lww.com
Of children with idiopathic nephrotic syndrome, 10%–20% fail to respond to steroids or
develop secondary steroid resistance (termed initial steroid sensitivity) and the majority …

A narrative review on C3 glomerulopathy: A rare renal disease

FP Schena, P Esposito, M Rossini - International journal of molecular …, 2020 - mdpi.com
In April 2012, a group of nephrologists organized a consensus conference in Cambridge
(UK) on type II membranoproliferative glomerulonephritis and decided to use a new …

Renal sarcoidosis

M Calatroni, G Moroni, F Reggiani, C Ponticelli - Journal of Nephrology, 2023 - Springer
Sarcoidosis is a systemic inflammatory disease of unknown etiology. The pathogenesis rests
on an aberrant T cell response to unidentified antigens in individuals predisposed by …

Focal segmental glomerulosclerosis: risk for recurrence and interventions to optimize outcomes following recurrence

LA Harshman, S Bartosh… - Pediatric Transplantation, 2022 - Wiley Online Library
Background FSGS is a common indication for kidney transplant with a high‐risk of
posttransplant recurrence. Methods In this review, we summarize current knowledge about …