MHC antigens and tumor escape from immune surveillance
F Garrido, I Algarra - 2001 - Elsevier
Publisher Summary The chapter presents that the primary and metastatic tumor cell growth
results from the development of sophisticated molecular and biological mechanisms that …
results from the development of sophisticated molecular and biological mechanisms that …
MHC/HLA class I loss in cancer cells
F Garrido, F Garrido - MHC class-I loss and cancer immune escape, 2019 - Springer
In this chapter I describe Tumour Immune Escape mechanisms associated with MHC/HLA
class I loss in human and experimental tumours. Different altered HLA class-I phenotypes …
class I loss in human and experimental tumours. Different altered HLA class-I phenotypes …
[HTML][HTML] What is trophoblast? A combination of criteria define human first-trimester trophoblast
Controversy surrounds reports describing the derivation of human trophoblast cells from
placentas and embryonic stem cells (ESC), partly due to the difficulty in identifying markers …
placentas and embryonic stem cells (ESC), partly due to the difficulty in identifying markers …
[HTML][HTML] HLA typing from RNA-Seq sequence reads
S Boegel, M Löwer, M Schäfer, T Bukur, J De Graaf… - Genome medicine, 2013 - Springer
We present a method, seq2HLA, for obtaining an individual's human leukocyte antigen
(HLA) class I and II type and expression using standard next generation sequencing RNA …
(HLA) class I and II type and expression using standard next generation sequencing RNA …
Frequent down-regulation of major histocompatibility class I antigen expression on individual micrometastatic carcinoma cells
K Pantel, G Schlimok, D Kutter, G Schaller, T Genz… - Cancer research, 1991 - AACR
An astoundingly high frequency of micrometastatic cells have been found in bone marrow
aspirates of patients with colon carcinomas (G. Schlimok et al., J. Clin. Oncol., 8: 831–837 …
aspirates of patients with colon carcinomas (G. Schlimok et al., J. Clin. Oncol., 8: 831–837 …
HLA-A-and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo …
NJ Stam, TM Vroom, PJ Peters… - International …, 1990 - academic.oup.com
The mAb HCA2 reacts preferentially with HLA-A locus heavy chains. Its reactivity contrasts
with that of HC1O, a mAb with more pronounced specificity for HLA-B and-C heavy chains …
with that of HC1O, a mAb with more pronounced specificity for HLA-B and-C heavy chains …
High frequency of altered HLA class I phenotypes in invasive breast carcinomas
T Cabrera, MA Fernandez, A Sierra, A Garrido… - Human immunology, 1996 - Elsevier
We studied 105 tumor samples obtained from patients diagnosed as having breast
carcinomas for HLA class I and II (DR) antigen expression, using a panel of mAbs defining …
carcinomas for HLA class I and II (DR) antigen expression, using a panel of mAbs defining …
Total loss of MHC class I is an independent indicator of good prognosis in breast cancer
Z Madjd, I Spendlove, SE Pinder… - … journal of cancer, 2005 - Wiley Online Library
Tumours can be recognised by CTL and NK cells. CTL recognition depends on expression
of MHC Class I loaded with peptides from tumour antigens. In contrast, loss of MHC Class I …
of MHC Class I loaded with peptides from tumour antigens. In contrast, loss of MHC Class I …
Loss of MHC class‐I expression in cervical carcinomas
ME Connor, PL Stern - International journal of cancer, 1990 - Wiley Online Library
The expression of MHC class‐I antigens was analysed in 67 cervical carcinoma biopsies;
16% of the biopsies showed complete or heterogeneous loss of HLA expression as judged …
16% of the biopsies showed complete or heterogeneous loss of HLA expression as judged …
[HTML][HTML] Guidelines for the diagnosis of antibody-mediated rejection in pancreas allografts—Updated Banff grading schema
The first Banff proposal for the diagnosis of pancreas rejection (Am J Transplant 2008; 8:
237) dealt primarily with the diagnosis of acute T-cell-mediated rejection (ACMR), while only …
237) dealt primarily with the diagnosis of acute T-cell-mediated rejection (ACMR), while only …