Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment

IA Yang, CR Jenkins, SS Salvi - The Lancet Respiratory Medicine, 2022 - thelancet.com
Chronic obstructive pulmonary disease (COPD) was traditionally thought to be caused by
tobacco smoking. However, recognition of the importance of non-smoking-related risk …

Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets

JM Leung, DD Sin - Bmj, 2017 - bmj.com
Asthma-COPD overlap syndrome (ACOS) or asthma-COPD overlap captures the subset of
patients with airways disease who have features of both asthma and chronic obstructive …

[HTML][HTML] Airway mucin concentration as a marker of chronic bronchitis

M Kesimer, AA Ford, A Ceppe… - … England Journal of …, 2017 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic
bronchitic and emphysematous components. In one biophysical model, the concentration of …

Global prevalence of asthma-COPD overlap (ACO) in the general population: a systematic review and meta-analysis

M Hosseini, A Almasi-Hashiani, M Sepidarkish… - Respiratory …, 2019 - Springer
Abstract Background Asthma-COPD overlap (ACO) is a term that encompasses patients with
features of both asthma and COPD. To date, the global prevalence of ACO in the general …

[PDF][PDF] Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity

K Tsuo, W Zhou, Y Wang, M Kanai, S Namba, R Gupta… - Cell genomics, 2022 - cell.com
Asthma is a complex disease that varies widely in prevalence across populations. The
extent to which genetic variation contributes to these disparities is unclear, as the genetics …

Phenotypes of COPD patients with a smoking history in Central and Eastern Europe: the POPE Study

V Koblizek, B Milenkovic, A Barczyk… - European …, 2017 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) represents a major health problem in
Central and Eastern European (CEE) countries; however, there are no data regarding …

Pathogenesis, clinical features of asthma COPD overlap, and therapeutic modalities

S Dey, MS Eapen, C Chia… - … of Physiology-Lung …, 2022 - journals.physiology.org
Both asthma and COPD are heterogeneous diseases identified by characteristic symptoms
and functional abnormalities, with airway obstruction common in both diseases. Asthma …

Update on asthma–COPD overlap (ACO): a narrative review

E Mekov, A Nuñez, DD Sin, M Ichinose… - … Journal of Chronic …, 2021 - Taylor & Francis
Although chronic obstructive pulmonary disease (COPD) and asthma are well-characterized
diseases, they can coexist in a given patient. The term asthma–COPD overlap (ACO) was …

Asthma-COPD Overlap in Clinical Practice (ACO_CP 2023): Toward Precision Medicine

AR Alsayed, MS Abu-Samak, M Alkhatib - Journal of Personalized …, 2023 - mdpi.com
Asthma and COPD have characteristic symptoms, yet patients with both are prevalent.
Despite this, there is currently no globally accepted definition for the overlap between …

Chronic obstructive pulmonary disease phenotypes: implications for care

S Mirza, R Benzo - Mayo Clinic Proceedings, 2017 - Elsevier
Chronic obstructive pulmonary disease (COPD) phenotyping can help define clusters of
patients with common characteristics that relate to clinically meaningful outcomes. In this …