Recent drug design strategies and identification of key heterocyclic scaffolds for promising anticancer targets

A Mushtaq, P Wu, MM Naseer - Pharmacology & Therapeutics, 2023 - Elsevier
Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …

Rational utilization of 1, 2, 3-triazole scaffold in anti-MRSA drug development: Design strategies, Structural insights and Pharmacological outcomes

A Singh, K Singh, A Sharma, J Kaur, R Kaur… - Journal of Molecular …, 2023 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is an important bacterial pathogen that
has the capability to cause mild to life-threatening infections. It has posed a significant threat …

Coumarin as an Elite Scaffold in Anti-Breast Cancer Drug Development: Design Strategies, Mechanistic Insights, and Structure–Activity Relationships

A Singh, K Singh, K Kaur, A Singh, A Sharma, K Kaur… - Biomedicines, 2024 - mdpi.com
Breast cancer is the most common cancer among women. Currently, it poses a significant
threat to the healthcare system due to the emerging resistance and toxicity of available drug …

Recent Developments in 1, 2, 3‐Triazole based α‐Glucosidase Inhibitors: Design Strategies, Structure‐activity Relationship and Mechanistic Insights

A Singh, K Singh, A Sharma, U Kaur… - Chemistry & …, 2024 - Wiley Online Library
Diabetes mellitus is a chronic and most prevalent metabolic disorder affecting 422 million
the people worldwide and causing life‐threatening associated conditions including …