Hazardous chemicals in the environment and diet or their electrophilic metabolites can form
adducts with genomic DNA, which can lead to mutations and the initiation of cancer. In …

Abstract The Working Group of the International Agency for Research on Cancer classified
the consumption of processed meat as carcinogenic to humans (Group 1), and classified red …

There are few studies on controlling the formation of heterocyclic amines (HAs) by adding
polyphenols to roasted lamb. The aim of this study was to assess the inhibitory effect of …

DNA adducts are believed to play a central role in the induction of cancer in cigarette
smokers and are proposed as being potential biomarkers of cancer risk. We have …

Heterocyclic aromatic amines (HAAs) form during the high-temperature cooking of meats,
poultry, and fish. Some HAAs also arise during the combustion of tobacco. HAAs are …

In human cells, the integrity of genetic information is constantly challenged by endogenous
and exogenous chemical agents that can induce DNA damage. To counteract the …

This study investigated the effects of smoke derived from cypress (CY), mulberry (MU),
metasequoia (ME), pine (PI), and camphor (CA) on the heterocyclic aromatic amines (HAs) …

Oxidative stress (OS) occurs when the production of reactive oxygen species (ROS)
overpowers the body's natural defence, causing macromolecular damage. The role of OS in …

Introduction Black men are diagnosed with prostate cancer at nearly twice the rate of white
men and are underrepresented in prostate cancer research, including validation studies of …

The eukaryotic global genomic nucleotide excision repair (GG-NER) pathway is the major
mechanism that removes most bulky and some nonbulky lesions from cellular DNA. There is …