Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities

C Hu, J Yang, Z Qi, H Wu, B Wang, F Zou, H Mei… - MedComm, 2022 - Wiley Online Library
The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …

[HTML][HTML] The pathophysiological role of heat shock response in autoimmunity: a literature review

A Androvitsanea, K Stylianou, E Drosataki, I Petrakis - Cells, 2021 - mdpi.com
Within the last two decades, there has been increasing evidence that heat-shock proteins
can have a differential influence on the immune system. They can either provoke or …

[HTML][HTML] DNAJB9 Is a Reliable Immunohistochemical Marker of Fibrillary Glomerulonephritis: Evaluation of Diagnostic Efficacy in a Large Series of Kidney Biopsies

A Gambella, C Pitino, A Barreca, A Nocifora, MM Giarin… - Biomedicines, 2022 - mdpi.com
Fibrillary glomerulonephritis (FGN) is a rare glomerular disease characterized by a
challenging diagnostic workup requiring ultrastructural identification of 20 nm-thick randomly …

Fibrillary glomerulonephritis, DNAJB9, and the unfolded protein response

NK Andeen, VL Kung, J Robertson, SB Gurley… - Glomerular …, 2022 - karger.com
Background: Fibrillary glomerulonephritis (FGN) is found in approximately 1% of native
kidney biopsies and was traditionally defined by glomerular deposition of fibrils larger than …