[HTML][HTML] Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations

RR Edwards, RH Dworkin, DC Turk, MS Angst… - Pain …, 2021 - journals.lww.com
There is tremendous interpatient variability in the response to analgesic therapy (even for
efficacious treatments), which can be the source of great frustration in clinical practice. This …

[HTML][HTML] Toward a mechanism-based approach to pain diagnosis

D Vardeh, RJ Mannion, CJ Woolf - The Journal of Pain, 2016 - Elsevier
The past few decades have witnessed a huge leap forward in our understanding of the
mechanistic underpinnings of pain, in normal states where it helps protect from injury, and …

[HTML][HTML] Quantitative sensory testing and predicting outcomes for musculoskeletal pain, disability, and negative affect: a systematic review and meta-analysis

V Georgopoulos, K Akin-Akinyosoye, W Zhang… - Pain, 2019 - journals.lww.com
Hypersensitivity due to central pain mechanisms can influence recovery and lead to worse
clinical outcomes, but the ability of quantitative sensory testing (QST), an index of …

The predictive value of quantitative sensory testing: a systematic review on chronic postoperative pain and the analgesic effect of pharmacological therapies in …

KK Petersen, HB Vaegter, A Stubhaug, A Wolff… - Pain, 2021 - journals.lww.com
Studies have suggested that quantitative sensory testing (QST) might hold a predictive value
for the development of chronic postoperative pain and the response to pharmacological …

Can quantitative sensory testing move us closer to mechanism-based pain management?

Y Cruz-Almeida, RB Fillingim - Pain medicine, 2014 - academic.oup.com
Objective This review summarizes the scientific literature relating to the use of quantitative
sensory testing (QST) for mechanism-based pain management. Design A literature search …

[HTML][HTML] Quantitative sensory testing to predict postoperative pain

M Braun, C Bello, T Riva, C Hönemann, D Doll… - Current pain and …, 2021 - Springer
Abstract Purpose of Review We review the relevance of quantitative sensory testing (QST) in
light of acute and chronic postoperative pain and associated challenges. Recent Findings …

[HTML][HTML] Are preoperative experimental pain assessments correlated with clinical pain outcomes after surgery? A systematic review

A Sangesland, C Støren, HB Vaegter - Scandinavian journal of pain, 2017 - degruyter.com
Background Pain after surgery is not uncommon with 30% of patients reporting moderate to
severe postoperative pain. Early identification of patients prone to postoperative pain may …

Somatosensory nociceptive characteristics differentiate subgroups in people with chronic low back pain: a cluster analysis

M Rabey, H Slater, P O'Sullivan, D Beales, A Smith - Pain, 2015 - journals.lww.com
The objectives of this study were to explore the existence of subgroups in a cohort with
chronic low back pain (n 5 294) based on the results of multimodal sensory testing and …

[HTML][HTML] Peripheral sensitization and loss of descending inhibition is a hallmark of chronic pruritus

EM Pogatzki-Zahn, MP Pereira, A Cremer… - Journal of Investigative …, 2020 - Elsevier
Neurophysiological mechanisms leading to chronicity of pruritus are not yet fully understood
and it is not known whether these mechanisms diverge between different underlying …

[HTML][HTML] Assessment of pain associated with chronic pancreatitis: An international consensus guideline

AM Drewes, CL van Veldhuisen, MD Bellin… - Pancreatology, 2021 - Elsevier
Pain is the most common symptom in chronic pancreatitis (CP) with a major impact on
quality of life. Few validated questionnaires to assess pain in CP exist, and the lack of …