[HTML][HTML] Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations
There is tremendous interpatient variability in the response to analgesic therapy (even for
efficacious treatments), which can be the source of great frustration in clinical practice. This …
efficacious treatments), which can be the source of great frustration in clinical practice. This …
[HTML][HTML] Toward a mechanism-based approach to pain diagnosis
The past few decades have witnessed a huge leap forward in our understanding of the
mechanistic underpinnings of pain, in normal states where it helps protect from injury, and …
mechanistic underpinnings of pain, in normal states where it helps protect from injury, and …
[HTML][HTML] Quantitative sensory testing and predicting outcomes for musculoskeletal pain, disability, and negative affect: a systematic review and meta-analysis
V Georgopoulos, K Akin-Akinyosoye, W Zhang… - Pain, 2019 - journals.lww.com
Hypersensitivity due to central pain mechanisms can influence recovery and lead to worse
clinical outcomes, but the ability of quantitative sensory testing (QST), an index of …
clinical outcomes, but the ability of quantitative sensory testing (QST), an index of …
The predictive value of quantitative sensory testing: a systematic review on chronic postoperative pain and the analgesic effect of pharmacological therapies in …
Studies have suggested that quantitative sensory testing (QST) might hold a predictive value
for the development of chronic postoperative pain and the response to pharmacological …
for the development of chronic postoperative pain and the response to pharmacological …
Can quantitative sensory testing move us closer to mechanism-based pain management?
Y Cruz-Almeida, RB Fillingim - Pain medicine, 2014 - academic.oup.com
Objective This review summarizes the scientific literature relating to the use of quantitative
sensory testing (QST) for mechanism-based pain management. Design A literature search …
sensory testing (QST) for mechanism-based pain management. Design A literature search …
[HTML][HTML] Quantitative sensory testing to predict postoperative pain
Abstract Purpose of Review We review the relevance of quantitative sensory testing (QST) in
light of acute and chronic postoperative pain and associated challenges. Recent Findings …
light of acute and chronic postoperative pain and associated challenges. Recent Findings …
[HTML][HTML] Are preoperative experimental pain assessments correlated with clinical pain outcomes after surgery? A systematic review
A Sangesland, C Støren, HB Vaegter - Scandinavian journal of pain, 2017 - degruyter.com
Background Pain after surgery is not uncommon with 30% of patients reporting moderate to
severe postoperative pain. Early identification of patients prone to postoperative pain may …
severe postoperative pain. Early identification of patients prone to postoperative pain may …
Somatosensory nociceptive characteristics differentiate subgroups in people with chronic low back pain: a cluster analysis
M Rabey, H Slater, P O'Sullivan, D Beales, A Smith - Pain, 2015 - journals.lww.com
The objectives of this study were to explore the existence of subgroups in a cohort with
chronic low back pain (n 5 294) based on the results of multimodal sensory testing and …
chronic low back pain (n 5 294) based on the results of multimodal sensory testing and …
[HTML][HTML] Peripheral sensitization and loss of descending inhibition is a hallmark of chronic pruritus
EM Pogatzki-Zahn, MP Pereira, A Cremer… - Journal of Investigative …, 2020 - Elsevier
Neurophysiological mechanisms leading to chronicity of pruritus are not yet fully understood
and it is not known whether these mechanisms diverge between different underlying …
and it is not known whether these mechanisms diverge between different underlying …
[HTML][HTML] Assessment of pain associated with chronic pancreatitis: An international consensus guideline
AM Drewes, CL van Veldhuisen, MD Bellin… - Pancreatology, 2021 - Elsevier
Pain is the most common symptom in chronic pancreatitis (CP) with a major impact on
quality of life. Few validated questionnaires to assess pain in CP exist, and the lack of …
quality of life. Few validated questionnaires to assess pain in CP exist, and the lack of …