Neuromodulation of hippocampal-prefrontal cortical synaptic plasticity and functional connectivity: implications for neuropsychiatric disorders

RN Ruggiero, MT Rossignoli, DB Marques… - Frontiers in cellular …, 2021 - frontiersin.org
The hippocampus-prefrontal cortex (HPC-PFC) pathway plays a fundamental role in
executive and emotional functions. Neurophysiological studies have begun to unveil the …

Input convergence, synaptic plasticity and functional coupling across hippocampal-prefrontal-thalamic circuits

LS Bueno-Junior, JP Leite - Frontiers in Neural Circuits, 2018 - frontiersin.org
Executive functions and working memory are long known to involve the prefrontal cortex
(PFC), and two PFC-projecting areas: midline/paramidline thalamus (MLT) and cornus …

Prediction of learned resistance or helplessness by hippocampal-prefrontal cortical network activity during stress

DB Marques, RN Ruggiero… - Journal of …, 2022 - Soc Neuroscience
The perception of control over a stressful experience may determine its impacts and
generate resistance against future stressors. Although the medial prefrontal cortex (PFC) …

Hippocampal network abnormalities explain amnesia after VGKCC-Ab related autoimmune limbic encephalitis

C Loane, GPD Argyropoulos… - Journal of Neurology …, 2019 - jnnp.bmj.com
Objective Limbic encephalitis associated with antibodies to components of the voltage-gated
potassium channel complex (VGKCC-Ab-LE) often leads to hippocampal atrophy and …

Manual hippocampal subfield segmentation using high-field MRI: impact of different subfields in hippocampal volume loss of temporal lobe epilepsy patients

JE Peixoto-Santos, LED Carvalho… - Frontiers in …, 2018 - frontiersin.org
In patients with temporal lobe epilepsy (TLE), presurgical magnetic resonance imaging
(MRI) often reveals hippocampal atrophy, while neuropathological assessment indicates the …

The ventral hippocampus is required for behavioral flexibility but not for allocentric/egocentric learning

A Torres-Berrío, V Vargas-López, M López-Canul - Brain research bulletin, 2019 - Elsevier
Behavioral flexibility is a complex cognitive function that allows for the rapid adaptation to a
changing environment. This ability is modulated by the proper function of the prefrontal …

Dysfunctional hippocampal-prefrontal network underlies a multidimensional neuropsychiatric phenotype following early-life seizure

RN Ruggiero, DB Marques, MT Rossignoli, JB De Ross… - Elife, 2024 - elifesciences.org
Brain disturbances during development can have a lasting impact on neural function and
behavior. Seizures during this critical period are linked to significant long-term …

Nitric oxide blockade in mediodorsal thalamus impaired nicotine/ethanol-induced memory retrieval in rats via inhibition of prefrontal cortical pCREB/CREB signaling …

F Karimani, L Delphi, A Rezayof - Neurobiology of learning and memory, 2019 - Elsevier
Reciprocal connections between the mediodorsal thalamic nucleus (MD) and the prefrontal
cortex (PFC) are important for memory processes. Since the co-abuse of nicotine and …

Altered responsiveness of the antioxidant system in chronically stressed animals: modulation by chronic lurasidone treatment

V Spero, MS Paladini, P Brivio, MA Riva… - …, 2022 - Springer
Rationale Although the occurrence of stressful events is very common during life, their
impact may be different depending on the experience severity and duration. Specifically …

Dissociable contributions of mediodorsal and anterior thalamic nuclei in visual attentional performance: A comparison using nicotinic and muscarinic cholinergic …

CP Mantanona, T Božič… - Journal of …, 2020 - journals.sagepub.com
Background: Thalamic subregions mediate various cognitive functions, including attention,
inhibitory response control and decision making. Such neuronal activity is modulated by …