Metabolic reprogramming in cancer cells: emerging molecular mechanisms and novel therapeutic approaches

C Navarro, Á Ortega, R Santeliz, B Garrido, M Chacín… - Pharmaceutics, 2022 - mdpi.com
The constant changes in cancer cell bioenergetics are widely known as metabolic
reprogramming. Reprogramming is a process mediated by multiple factors, including …

Targeting autophagy and lipid metabolism in cancer stem cells

B Chakravarti, JA Siddiqui, RA Sinha, S Raza - Biochemical pharmacology, 2023 - Elsevier
Cancer stem cells (CSCs) are a subset of cancer cells with self-renewal ability and tumor
initiating properties. Unlike the other non-stem cancer cells, CSCs resist traditional therapy …

Resveratrol suppresses lung cancer by targeting cancer stem-like cells and regulating tumor microenvironment

C Xie, C Liang, R Wang, K Yi, X Zhou, X Li… - The Journal of …, 2023 - Elsevier
Increasing evidence indicate that cancer stem cells (CSCs) are the key driver of tumor
initiation and recurrence. The cellular and soluble components of the tumor …

Metabolic adaptations in cancer stem cells: A key to therapy resistance

M Masoudi, D Moti, R Masoudi, A Auwal… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Cancer stem cells (CSCs) are a subset of tumor cells that can initiate and sustain tumor
growth and cause recurrence and metastasis. CSCs are particularly resistant to …

The lipid droplet in cancer: From being a tumor‐supporting hallmark to clinical therapy

Y Cui, S Man, J Tao, Y Liu, L Ma, L Guo… - Acta …, 2024 - Wiley Online Library
Introduction Abnormal lipid metabolism, one of the hallmarks in cancer, has gradually
emerged as a novel target for cancer treatment. As organelles that store and release excess …

Mechanism of cancer stemness maintenance in human liver cancer

N Liang, T Yang, Q Huang, P Yu, C Liu, L Chen… - Cell death & …, 2022 - nature.com
Primary liver cancer mainly includes the following four types: hepatocellular carcinoma
(HCC), cholangiocarcinoma (CCA), hepatoblastoma (HB), and combined hepatocellular …

Role of the bone marrow microenvironment in multiple myeloma treatment using CAR-T therapy

H Yao, L Cheng, D Chen, Q Zhang, L Qiu… - Expert Review of …, 2023 - Taylor & Francis
Introduction Multiple myeloma (MM) is a malignant tumor caused by abnormal proliferation
of bone marrow (BM) plasma cells and is the second most common hematologic …

Evolving Diagnostic and Treatment Strategies for Pediatric CNS Tumors: The Impact of Lipid Metabolism

P Fernández-García, G Malet-Engra, M Torres… - Biomedicines, 2023 - mdpi.com
Pediatric neurological tumors are a heterogeneous group of cancers, many of which carry a
poor prognosis and lack a “standard of care” therapy. While they have similar anatomic …

[PDF][PDF] Metabolic reprogramming in cancer cells: emerging molecular mechanisms and novel therapeutic approaches. Pharmaceutics. 2022; 14: 1303

C Navarro, Á Ortega, R Santeliz, B Garrido, M Chacín… - 2022 - academia.edu
The constant changes in cancer cell bioenergetics are widely known as metabolic
reprogramming. Reprogramming is a process mediated by multiple factors, including …

Effects of the Combined Treatment with a G-Quadruplex-Stabilizing Ligand and Photon Beams on Glioblastoma Stem-like Cells: A Magnetic Resonance Study

A Palma, S Grande, AM Luciani, L Ricci-Vitiani… - International Journal of …, 2021 - mdpi.com
Glioblastoma multiforme is a malignant primary brain tumor with a poor prognosis and high
rates of chemo-radiotherapy failure, mainly due to a small cell fraction with stem-like …