[HTML][HTML] Overview of the potential use of fluvoxamine for COVID-19 and long COVID

K Hashimoto - Discover Mental Health, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has presented a serious worldwide threat to
public health since its emergence in late 2019. From a safety point of view, drug repurposing …

[HTML][HTML] Efficacy and safety of fluvoxamine for the treatment of COVID-19 patients: a systematic review and meta-analysis

HA Cheema, U Jafar, AA Elrashedy… - The Journal of …, 2022 - ncbi.nlm.nih.gov
A recent letter in this journal described an avian influenza virus of wild bird origin that is well
adapted to a mammalian host, posing a potential threat to animal and human health. 1 This …

[HTML][HTML] Time to stop using ineffective COVID-19 drugs

SS Abdool Karim, N Devnarain - New England Journal of …, 2022 - Mass Medical Soc
In practicing evidence-based medicine, physicians use the best evidence currently available
on safety and efficacy in making decisions on treatment choices for their patients. During the …

[HTML][HTML] Impact of fluvoxamine on outpatient treatment of COVID-19 in Honduras in a prospective observational real-world study

E Pineda, J Singh, MV Pineda, JG Umanzor… - Frontiers in …, 2022 - frontiersin.org
Background: The COVID-19 pandemic has impacted millions of lives globally. While COVID-
19 did not discriminate against developed or developing nations, it has been a significant …

Molecular Simulation of the Effect of Electron Donor/Acceptor Groups on Fluvoxamine/Serotonin Interactions as a Strategy for COVID‐19 Mitigation

H Hadi, H Louis, K Jafari, TE Gber… - …, 2023 - Wiley Online Library
Fluvoxamine has been proven in studies to improve the immune system by reabsorbing
serotonin and to be beneficial in limiting the spread of covid‐19 (in the early stages of the …

Acid sphingomyelinase (ASM) and COVID‐19: A review of the potential use of ASM inhibitors against SARS‐CoV‐2

PJT Pauletto, CP Delgado… - Cell Biochemistry and …, 2023 - Wiley Online Library
In the last 2 years, different pharmacological agents have been indicated as potential
inhibitors of SARS‐CoV‐2 in vitro. Specifically, drugs termed as functional inhibitors of acid …

[HTML][HTML] Molecular bases of serotonin reuptake inhibitor antidepressant-attributed effects in COVID-19: A new insight on the role of bradykinins

AS Gouda, B Mégarbane - Journal of Personalized Medicine, 2022 - mdpi.com
Widely available effective drugs to treat coronavirus disease-2019 (COVID-19) are still
limited. Various studies suggested the potential contribution of selective serotonin-reuptake …

Characterization of tritiated JNJ‐GluN2B‐5 (3‐[3H] 1‐(azetidin‐1‐yl)‐2‐(6‐(4‐fluoro‐3‐methyl‐phenyl)pyrrolo[3,2‐b]pyridin‐1‐yl)ethanone), a high affinity GluN2B …

J Schoellerman, B Lord, A Bhattacharya… - Journal of …, 2024 - Wiley Online Library
Here, we describe the characterization of a radioligand selective for GluN2B‐containing
NMDA receptors, 3‐[3H] 1‐(azetidin‐1‐yl)‐2‐(6‐(4‐fluoro‐3‐methyl‐phenyl) pyrrolo [3, 2‐b] …

Antiviral Treatment of Coronavirus Disease-2019 Pneumonia

C Radcliffe, M Malinis, MM Azar - Clinics in Chest …, 2023 - chestmed.theclinics.com
With 614 million cumulative cases and over 6.3 million deaths worldwide as of September
30, 2022, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic …

[HTML][HTML] The efficacy and safety of fluvoxamine in patients with COVID-19: A systematic review and meta-analysis from randomized controlled trials

Q Zhou, G Zhao, Y Pan, Y Zhang, Y Ni - Plos one, 2024 - journals.plos.org
Background Recently, several randomized controlled trials (RCTs) of fluvoxamine have
been successfully conducted for the treatment of patients with coronavirus disease 2019 …