Astrocytes are essential for the development and homeostatic maintenance of the central
nervous system (CNS). They are also critical players in the CNS injury response during …

Spinal cord injury (SCI) triggers a complex cascade of molecular and chemical events that
leads to progressive cell loss and tissue damage. 1, 2 Nearly a century of fundamental basic …

Multiple sclerosis is a chronic inflammatory disease of the central nervous system.
Astrocytes are heterogeneous glial cells that are resident in the central nervous system and …

The glial environment influences neurological disease progression, yet much of our
knowledge still relies on preclinical animal studies, especially regarding astrocyte …

Astrocytes in the adult brain show cellular plasticity; however, whether they have the
potential to generate multiple lineages remains unclear. Here, we perform in vivo screens …

The concept of the neurovascular unit emphasizes the importance of cell-cell signaling
between neural, glial, and vascular compartments. In neurogenesis, for example, brain …

In the central nervous system (CNS), glial cells, such as microglia and astrocytes, are
normally associated with support roles including contributions to energy metabolism …

Traumatic Brain Injury (TBI) represents a significant health concern, necessitating advanced
therapeutic interventions. This detailed review explores the critical roles of astrocytes, key …

Spinal cord ependymal cells display neural stem cell properties in vitro and generate scar-
forming astrocytes and remyelinating oligodendrocytes after injury. We report that …

Regenerative medicine harnesses the body's innate capacity for self-repair to restore
malfunctioning tissues and organs. Stem cell therapies represent a key regenerative …