Cancer is a devastating disease and is the second leading cause of death worldwide.
Surgery, chemotherapy (CT), and/or radiation therapy (RT) are the treatment of choice for …

Abstract β-Lapachone is an ortho-naphthoquinone originally isolated from the heartwood of
Handroanthus impetiginosus and can be obtained through synthesis from lapachol …

Worldwide, metastatic spread of tumor is the major cause of cancer-related deaths. There
are many anti-metastatic agents that can target metastasis-related pathways, but there are …

Despite ortho-quinones showing several biological and pharmacological activities, there is
still a lack of biophysical characterization of their interaction with albumin-the main carrier of …

Cellular redox status has been considered as a focal point for the pathogenesis of multiple
disorders. High and persistent levels of free radicals kick off inflammation and associated …

The structural motif of coumarins is related with various biological activities and
pharmacological properties. Both natural coumarin extracted from various plants or a new …

We and others propose vimentin as a possible cellular target for the treatment of COVID-19.
This innovative idea is so recent that it requires further attention and debate. The significant …

β-sitosterol (SITO) has been reported with anticancer effects; however, with poor
bioavailability. The current study aimed to investigate whether liposomal encapsulated β …

Traditional herbal medicine (THM) is a “core” from which modern medicine has evolved over
time. Besides this, one third of people worldwide have no access to modern medicine and …

Obesity is a global public health issue. Obesity-related chronic low-grade inflammation
(meta-inflammation) can lead to aberrant adipokine release and promote cardiometabolic …