[HTML][HTML] Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches
Y Jin, W Ji, H Yang, S Chen, W Zhang… - Signal transduction and …, 2020 - nature.com
On 12 March 2020, the outbreak of coronavirus disease 2019 (COVID-19) was declared a
pandemic by the World Health Organization. As of 4 August 2020, more than 18 million …
pandemic by the World Health Organization. As of 4 August 2020, more than 18 million …
[HTML][HTML] Role of C-reactive protein at sites of inflammation and infection
NR Sproston, JJ Ashworth - Frontiers in immunology, 2018 - frontiersin.org
C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at
sites of infection or inflammation. CRP is produced as a homopentameric protein, termed …
sites of infection or inflammation. CRP is produced as a homopentameric protein, termed …
Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial …
O Kleveland, G Kunszt, M Bratlie, T Ueland… - European heart …, 2016 - academic.oup.com
Abstract Aims Interleukin-6 (IL-6) contributes to atherosclerotic plaque destabilization and is
involved in myocardial injury during ischaemia–reperfusion. Interleukin-6 is therefore a …
involved in myocardial injury during ischaemia–reperfusion. Interleukin-6 is therefore a …
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I
Atherosclerotic cardiovascular disease results in> 19 million deaths annually, and coronary
heart disease accounts for the majority of this toll. Despite major advances in treatment of …
heart disease accounts for the majority of this toll. Despite major advances in treatment of …
Cardiovascular risk factors and molecular routes underlying endothelial dysfunction: Novel opportunities for primary prevention
G Benincasa, E Coscioni, C Napoli - Biochemical Pharmacology, 2022 - Elsevier
One of the major challenges of cardiovascular primary prevention approach is the absence
of early biomarkers of endothelial dysfunction which may be useful for identifying at-risk …
of early biomarkers of endothelial dysfunction which may be useful for identifying at-risk …
Mortality in COPD: role of comorbidities
DD Sin, NR Anthonisen, JB Soriano… - European Respiratory …, 2006 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) represents an increasing burden throughout
the world. COPD-related mortality is probably underestimated because of the difficulties …
the world. COPD-related mortality is probably underestimated because of the difficulties …
C-reactive protein and the risk of developing hypertension
HD Sesso, JE Buring, N Rifai, GJ Blake, JM Gaziano… - Jama, 2003 - jamanetwork.com
ContextAlthough it has been hypothesized that hypertension is in part an inflammatory
disorder, clinical data linking inflammation with incident hypertension are scarce …
disorder, clinical data linking inflammation with incident hypertension are scarce …
Adipokines: molecular links between obesity and atheroslcerosis
DCW Lau, B Dhillon, H Yan… - American Journal of …, 2005 - journals.physiology.org
Atherosclerotic disease remains the leading cause of death in industrialized nations despite
major advances in its diagnosis, treatment, and prevention. The increasing epidemic of …
major advances in its diagnosis, treatment, and prevention. The increasing epidemic of …
A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis
Background—Given the central importance of nitric oxide (NO) in the development and
clinical course of cardiovascular diseases, we sought to determine whether the powerful …
clinical course of cardiovascular diseases, we sought to determine whether the powerful …
Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study
A Kalogeropoulos, V Georgiopoulou, BM Psaty… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to evaluate the association between inflammation
and heart failure (HF) risk in older adults. Background: Inflammation is associated with HF …
and heart failure (HF) risk in older adults. Background: Inflammation is associated with HF …