Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds

HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

Biological function of long non-coding RNA (LncRNA) Xist

W Wang, L Min, X Qiu, X Wu, C Liu, J Ma… - Frontiers in cell and …, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) regulate gene expression in a variety of ways at
epigenetic, chromatin remodeling, transcriptional, and translational levels. Accumulating …

m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to …

D Jin, J Guo, Y Wu, J Du, L Yang, X Wang, W Di… - Journal of hematology & …, 2019 - Springer
Background METTL3 is an RNA methyltransferase that mediates m 6 A modification and is
implicated in mRNA biogenesis, decay, and translation. However, the biomechanism …

Blood-based cancer biomarkers in liquid biopsy: a promising non-invasive alternative to tissue biopsy

J Marrugo-Ramírez, M Mir, J Samitier - International journal of molecular …, 2018 - mdpi.com
Cancer is one of the greatest threats facing our society, being the second leading cause of
death globally. Currents strategies for cancer diagnosis consist of the extraction of a solid …

Circular RNA: a new star of noncoding RNAs

S Qu, X Yang, X Li, J Wang, Y Gao, R Shang, W Sun… - Cancer letters, 2015 - Elsevier
Circular RNAs (circRNAs) are a novel type of RNA that, unlike linear RNAs, form a
covalently closed continuous loop and are highly represented in the eukaryotic …

The functions and unique features of LncRNAs in cancer development and tumorigenesis

K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …

Long non-coding RNAs and complex diseases: from experimental results to computational models

X Chen, CC Yan, X Zhang, ZH You - Briefings in bioinformatics, 2017 - academic.oup.com
LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …

[HTML][HTML] Emerging roles of circRNA in formation and progression of cancer

Y Yin, J Long, Q He, Y Li, Y Liao, P He, W Zhu - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are recently discovered as a special novel type of endogenous
noncoding RNAs (ncRNAs), which form a covalently closed continuous loop and are highly …

Long noncoding RNA MALAT1 promotes aggressive renal cell carcinoma through Ezh2 and interacts with miR-205

H Hirata, Y Hinoda, V Shahryari, G Deng, K Nakajima… - Cancer research, 2015 - AACR
Recently, long noncoding RNAs (lncRNA) have emerged as new gene regulators and
prognostic markers in several cancers, including renal cell carcinoma (RCC). In this study …

LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer

A Bhan, SS Mandal - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
Non-coding RNAs (ncRNAs) are emerging classes of regulatory RNA that play key roles in
various cellular and physiological processes such as in gene regulation, chromatin …