Arginine (L-arginine), is an amino acid involved in a number of biological processes,
including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide …

GPCRs (G-protein [guanine nucleotide-binding protein]–coupled receptors) play a central
physiological role in the regulation of cardiac function in both health and disease and thus …

New vessel formation inside the arterial wall and atherosclerotic plaques plays a critical role
in pathogenesis of heart attacks and strokes. The 2 known mechanisms resulting in the …

With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift
in the concept of neoangiogenesis occurred. The identification of circulating EPCs in …

Infantile haemangiomas (IH) are the most common benign tumours of infancy. Although
most IH are innocuous and 85–90% regress spontaneously, some may become life‐or …

OBJECTIVE: Infantile hemangiomas (IHs) are the most-common soft-tissue tumors of
infancy. We report the use of propranolol to control the growth phase of IHs. METHODS …

Peripheral arterial disease (PAD) affects 5 million people in the US and is the primary cause
of limb amputations. Exercise remains the single best intervention for PAD, in part thought to …

Retinopathy of prematurity (ROP) is a disease that can cause blindness in very low
birthweight infants. The incidence of ROP is closely correlated with the weight and the …

Gene therapy is a promising modality for the treatment of inherited and acquired
cardiovascular diseases. The identification of the molecular pathways involved in the …

Drugs currently approved to coat stents used in percutaneous coronary interventions do not
discriminate between proliferating vascular smooth muscle cells (VSMCs) and endothelial …