Brain aging mechanisms with mechanical manifestations
Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
Imaging of normal brain aging
Brain aging is mainly characterized by physiologic changes that reduce cognitive abilities,
by decreased physical fitness, and by increased mortality. 1 Functional decline, such as …
by decreased physical fitness, and by increased mortality. 1 Functional decline, such as …
Reduced white matter venous density on MRI is associated with neurodegeneration and cognitive impairment in the elderly
High-resolution susceptibility weighted imaging (SWI) provides unique contrast to small
venous vasculature. The conspicuity of these mesoscopic veins, such as deep medullary …
venous vasculature. The conspicuity of these mesoscopic veins, such as deep medullary …
3D finite-element brain modeling of lateral ventricular wall loading to rationalize periventricular white matter hyperintensity locations
A Caçoilo, H Rusinek, J Weickenmeier - Engineering with computers, 2022 - Springer
Aging-related periventricular white matter hyperintensities (pvWMHs) are a common
observation in medical images of the aging brain. The underlying tissue damage is part of …
observation in medical images of the aging brain. The underlying tissue damage is part of …
Peak ependymal cell stretch overlaps with the onset locations of periventricular white matter lesions
VL Visser, H Rusinek, J Weickenmeier - Scientific Reports, 2021 - nature.com
Deep and periventricular white matter hyperintensities (dWMH/pvWMH) are bright
appearing white matter tissue lesions in T2-weighted fluid attenuated inversion recovery …
appearing white matter tissue lesions in T2-weighted fluid attenuated inversion recovery …
Cortical thickness and brain connectivity mediate the relation between white matter hyperintensity and information processing speed in cerebral small vessel disease
White matter hyperintensities of presumed vascular origin (WMH) are the most common
imaging feature of cerebral small vessel disease (cSVD) and are associated with cognitive …
imaging feature of cerebral small vessel disease (cSVD) and are associated with cognitive …
Longitudinal Changes in Global Cerebral Blood Flow in Cognitively Normal Older Adults: A Phase‐Contrast MRI Study
Background Characterization of blood supply changes in older individuals is important in
understanding brain aging and diseases. However, prior studies largely focused on cross …
understanding brain aging and diseases. However, prior studies largely focused on cross …
Cocaine use may moderate the associations of HIV and female sex with neurocognitive impairment in a predominantly african American population disproportionately …
H Lai, DD Celentano, G Treisman, J Khalsa… - AIDS patient care and …, 2023 - liebertpub.com
HIV-associated neurocognitive disorders (HAND) remain a major challenge for people with
HIV in the antiretroviral therapy era. Cocaine use may trigger/exacerbate HAND among …
HIV in the antiretroviral therapy era. Cocaine use may trigger/exacerbate HAND among …
[HTML][HTML] Associations between cerebral blood flow and progression of white matter hyperintensity in community-dwelling adults: a longitudinal cohort study
H Han, Z Ning, D Yang, M Yu, H Qiao… - … Imaging in Medicine …, 2022 - ncbi.nlm.nih.gov
Background White matter hyperintensity (WMH) is prevalent in elderly populations. Ischemia
is characterized by a decline in cerebral blood flow (CBF) and may play a key role in the …
is characterized by a decline in cerebral blood flow (CBF) and may play a key role in the …
A multiphysics model to predict periventricular white matter hyperintensity growth during healthy brain aging
A Caçoilo, B Dortdivanlioglu, H Rusinek… - Brain multiphysics, 2023 - Elsevier
Periventricular white matter hyperintensities (WMH) are a common finding in medical
images of the aging brain and are associated with white matter damage resulting from …
images of the aging brain and are associated with white matter damage resulting from …