[HTML][HTML] Differential gene expression analysis pipelines and bioinformatic tools for the identification of specific biomarkers: A review
D Rosati, M Palmieri, G Brunelli, A Morrione… - Computational and …, 2024 - Elsevier
In recent years, the role of bioinformatics and computational biology together with omics
techniques and transcriptomics has gained tremendous importance in biomedicine and …
techniques and transcriptomics has gained tremendous importance in biomedicine and …
[HTML][HTML] Enzyme Databases in the Era of Omics and Artificial Intelligence
U Prešern, M Goličnik - International Journal of Molecular Sciences, 2023 - mdpi.com
Enzyme research is important for the development of various scientific fields such as
medicine and biotechnology. Enzyme databases facilitate this research by providing a wide …
medicine and biotechnology. Enzyme databases facilitate this research by providing a wide …
[HTML][HTML] ChatGPT usage in the Reactome curation process
K Tiwari, L Matthews, B May, V Shamovsky… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Appreciating the rapid advancement and ubiquity of generative AI, particularly ChatGPT, a
chatbot using large language models like GPT, we endeavour to explore the potential …
chatbot using large language models like GPT, we endeavour to explore the potential …
[HTML][HTML] Identification of biomarkers and immune infiltration characterization of lipid metabolism-associated genes in osteoarthritis based on machine learning …
Y Ma, Y Liu, D Luo, Z Guo, H Xiang, B Chen… - Aging (Albany NY …, 2024 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a prevalent degenerative condition commonly observed in the elderly,
leading to consequential disability. Despite notable advancements made in clinical …
leading to consequential disability. Despite notable advancements made in clinical …
[HTML][HTML] Proteomic Insights into Osteoporosis: Unraveling Diagnostic Markers of and Therapeutic Targets for the Metabolic Bone Disease
J Wang, M Xue, Y Hu, J Li, Z Li, Y Wang - Biomolecules, 2024 - mdpi.com
Osteoporosis (OP), a prevalent skeletal disorder characterized by compromised bone
strength and increased susceptibility to fractures, poses a significant public health concern …
strength and increased susceptibility to fractures, poses a significant public health concern …
Pathway-based, reaction-specific annotation of disease variants for elucidation of molecular phenotypes
M Orlic-Milacic, K Rothfels, L Matthews, A Wright… - Database, 2023 - academic.oup.com
Germline and somatic mutations can give rise to proteins with altered activity, including both
gain and loss-of-function. The effects of these variants can be captured in disease-specific …
gain and loss-of-function. The effects of these variants can be captured in disease-specific …
Unsupervised generative AI discovers pan-leukocyte dysregulated pathways in single-cell lupus data
H Bolouri, K Cerosaletti, A Lacy-Hulbert - bioRxiv, 2024 - biorxiv.org
Comparisons of single-cell RNA-sequencing (scRNA-seq) data from healthy and diseased
tissues are widely used to identify cell-type-specific dysregulated genes, pathways, and …
tissues are widely used to identify cell-type-specific dysregulated genes, pathways, and …