The mechanisms of air pollution and particulate matter in cardiovascular diseases

A Fiordelisi, P Piscitelli, B Trimarco, E Coscioni… - Heart failure …, 2017 - Springer
Clinical and epidemiological studies demonstrate that short-and long-term exposure to air
pollution increases mortality due to respiratory and cardiovascular diseases. Given the …

[HTML][HTML] Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases

BNM Zordoky, IM Robertson, JRB Dyck - Biochimica et Biophysica Acta …, 2015 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Despite advancements in
diagnosis and treatment of cardiovascular disease, the incidence of cardiovascular disease …

[HTML][HTML] The role of the autophagy in myocardial ischemia/reperfusion injury

S Ma, Y Wang, Y Chen, F Cao - … et Biophysica Acta (BBA)-Molecular Basis …, 2015 - Elsevier
Autophagy is an intracellular process responsible for damaged or unnecessary protein and
organelle degradation. In the heart, autophagy occurs at basal level and dysregulated …

HIF-1α and PFKFB3 mediate a tight relationship between proinflammatory activation and anerobic metabolism in atherosclerotic macrophages

A Tawakol, P Singh, M Mojena… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—Although it is accepted that macrophage glycolysis is upregulated under hypoxic
conditions, it is not known whether this is linked to a similar increase in macrophage …

Advances in nanomedicines for diagnosis of central nervous system disorders

X Zhang, J Zhou, Z Gu, H Zhang, Q Gong, K Luo - Biomaterials, 2021 - Elsevier
In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …

Ischemic conditioning-induced endogenous brain protection: applications pre-, per-or post-stroke

Y Wang, C Reis, R Applegate II, G Stier, R Martin… - Experimental …, 2015 - Elsevier
In the area of brain injury and neurodegenerative diseases, a plethora of experimental and
clinical evidence strongly indicates the promise of therapeutically exploiting the endogenous …

Sex‐based differences in outcomes after percutaneous coronary intervention for acute myocardial infarction: a report from TRANSLATE‐ACS

CN Hess, LA McCoy, HJ Duggirala… - Journal of the …, 2014 - Am Heart Assoc
Background Data regarding sex‐based outcomes after percutaneous coronary intervention
(PCI) for myocardial infarction are mixed. We sought to examine whether sex differences in …

A relative L‐arginine deficiency contributes to endothelial dysfunction across the stages of the menopausal transition

J Klawitter, KL Hildreth, U Christians… - Physiological …, 2017 - Wiley Online Library
Vascular endothelial function declines across the menopause transition in women. We
tested the hypothesis that reduced availability of the endothelial nitric oxide synthase [eNOS] …

MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas

RA Kore, X Wang, Z Ding, RJ Griffin, AJ Tackett… - Molecular and cellular …, 2021 - Springer
Mesenchymal stem cell (MSC) exosomes may limit cardiac injury, and even reverse cardiac
damage in animal models of ischemia. To understand exosome-mediated improvement in …

Chemoreception and neuroplasticity in respiratory circuits

WH Barnett, AP Abdala, JFR Paton, IA Rybak… - Experimental …, 2017 - Elsevier
The respiratory central pattern generator must respond to chemosensory cues to maintain
oxygen (O 2) and carbon dioxide (CO 2) homeostasis in the blood and tissues. To do this …