Host and viral determinants of influenza A virus species specificity
Influenza A viruses cause pandemics when they cross between species and an
antigenically novel virus acquires the ability to infect and transmit between these new hosts …
antigenically novel virus acquires the ability to infect and transmit between these new hosts …
Small RNA-based antimicrobial immunity
Protection against microbial infection in eukaryotes is provided by diverse cellular and
molecular mechanisms. Here, we present a comparative view of the antiviral activity of virus …
molecular mechanisms. Here, we present a comparative view of the antiviral activity of virus …
Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis
AJW Te Velthuis, E Fodor - Nature Reviews Microbiology, 2016 - nature.com
The genomes of influenza viruses consist of multiple segments of single-stranded negative-
sense RNA. Each of these segments is bound by the heterotrimeric viral RNA-dependent …
sense RNA. Each of these segments is bound by the heterotrimeric viral RNA-dependent …
Protein coding and long noncoding RNA (lncRNA) transcriptional landscape in SARS-CoV-2 infected bronchial epithelial cells highlight a role for interferon and …
The global spread of COVID-19, caused by pathogenic severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) underscores the need for an imminent response from medical …
coronavirus 2 (SARS-CoV-2) underscores the need for an imminent response from medical …
SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease (COVID-19), continues to be a pressing health concern. In this study …
coronavirus disease (COVID-19), continues to be a pressing health concern. In this study …
Influenza A viruses: new research developments
RA Medina, A García-Sastre - Nature Reviews Microbiology, 2011 - nature.com
Influenza A viruses are zoonotic pathogens that continuously circulate and change in
several animal hosts, including birds, pigs, horses and humans. The emergence of novel …
several animal hosts, including birds, pigs, horses and humans. The emergence of novel …
The interplay between viral-derived miRNAs and host immunity during infection
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene
expression during cellular processes. The host-encoded miRNAs are known to modulate the …
expression during cellular processes. The host-encoded miRNAs are known to modulate the …
Extreme heterogeneity of influenza virus infection in single cells
Viral infection can dramatically alter a cell's transcriptome. However, these changes have
mostly been studied by bulk measurements on many cells. Here we use single-cell mRNA …
mostly been studied by bulk measurements on many cells. Here we use single-cell mRNA …
Prediction and analysis of SARS-CoV-2-targeting MicroRNA in human lung epithelium
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus, is
responsible for the coronavirus disease 2019 (COVID-19) pandemic of 2020. Experimental …
responsible for the coronavirus disease 2019 (COVID-19) pandemic of 2020. Experimental …
Common and unique features of viral RNA-dependent polymerases
AJW Te Velthuis - Cellular and molecular life sciences, 2014 - Springer
Eukaryotes and bacteria can be infected with a wide variety of RNA viruses. On average,
these pathogens share little sequence similarity and use different replication and …
these pathogens share little sequence similarity and use different replication and …