The complexities of malaria disease manifestations with a focus on asymptomatic malaria

DD Laishram, PL Sutton, N Nanda, VL Sharma… - Malaria journal, 2012 - Springer
Malaria is a serious parasitic disease in the developing world, causing high morbidity and
mortality. The pathogenesis of malaria is complex, and the clinical presentation of disease …

Understanding P. falciparum Asymptomatic Infections: A Proposition for a Transcriptomic Approach

KM Kimenyi, K Wamae, LI Ochola-Oyier - Frontiers in Immunology, 2019 - frontiersin.org
Malaria is still a significant public health burden in the tropics. Infection with malaria causing
parasites results in a wide range of clinical disease presentations, from severe to …

Plasmodium falciparum msp1 and msp2 genetic diversity and allele frequencies in parasites isolated from symptomatic malaria patients in Bobo-Dioulasso, Burkina …

AF Somé, T Bazié, I Zongo, RS Yerbanga, F Nikiéma… - Parasites & vectors, 2018 - Springer
Abstract Background In Burkina Faso, malaria remains the overall leading cause of
morbidity and mortality accounting for 35.12% of consultations, 40.83% of hospitalizations …

Determinants of Plasmodium falciparum multiplicity of infection and genetic diversity in Burkina Faso

P Sondo, K Derra, T Rouamba, S Nakanabo Diallo… - Parasites & vectors, 2020 - Springer
Background Investigating malaria transmission dynamics is essential to inform policy
decision making. Whether multiplicity of infection (MOI) dynamic from individual infections …

Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite, Plasmodium falciparum

AE Barry, L Schultz, CO Buckee, JC Reeder - PLoS One, 2009 - journals.plos.org
The extensive diversity of Plasmodium falciparum antigens is a major obstacle to a broadly
effective malaria vaccine but population genetics has rarely been used to guide vaccine …

Genetic diversity of Plasmodium falciparum and genetic profile in children affected by uncomplicated malaria in Cameroon

TN Metoh, JH Chen, P Fon-Gah, X Zhou… - Malaria Journal, 2020 - Springer
Background Malaria is a major public health problem in Cameroon. The study of the genetic
diversity within parasite population is essential for understanding the mechanism underlying …

Genetic diversity of Plasmodium falciparum isolates from Pahang, Malaysia based on MSP-1 and MSP-2 genes

WM Atroosh, HM Al-Mekhlafi, MAK Mahdy, R Saif-Ali… - Parasites & vectors, 2011 - Springer
Background Malaria is still a public health problem in Malaysia especially in the interior
parts of Peninsular Malaysia and the states of Sabah and Sarawak (East Malaysia). This is …

Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics

G Sirugo, BJ Hennig, AA Adeyemo, A Matimba… - Human genetics, 2008 - Springer
Africa is the ultimate source of modern humans and as such harbors more genetic variation
than any other continent. For this reason, studies of the patterns of genetic variation in …

Asymptomatic malaria infection prevailing risks for human health and malaria elimination

D Prusty, N Gupta, A Upadhyay, A Dar, B Naik… - Infection, Genetics and …, 2021 - Elsevier
There has been a consistent rise in malaria cases in the last few years. The existing malaria
control measures are challenged by insecticide resistance in the mosquito vector, drug …

[HTML][HTML] Drug use practices and self-treatment for suspected malaria in Ibadan, Nigeria

OJ Bamikole, TH Olajide, BA Adedeji… - The American Journal …, 2023 - ncbi.nlm.nih.gov
Antimalarial drug failures have been reported anecdotally in Nigeria, and malarial self-
treatment practices could be a contributing factor. This study was designed to assess the …